Ignite Creation Date:
2024-05-05 @ 12:08 PM
Last Modification Date:
2024-10-26 @ 9:21 AM
Study NCT ID:
NCT00256438
Status:
UNKNOWN
Last Update Posted:
2006-07-10
First Post:
2005-11-17
Brief Title:
Depression and Transcranial Direct Current Stimulation tDCS
Sponsor:
The University of New South Wales
Organization:
The University of New South Wales
Study Overview
Official Title:
The Treatment of Depression Using Transcranial Direct Current Stimulation tDCS a Pilot Study
Status:
UNKNOWN
Status Verified Date:
2006-07
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Transcranial direct current stimulation tDCSis a non invasive technique which uses a very weak current to change excitability in targeted regions of the brain Early studies suggest that it has antidepressant properties This study will test the safety and efficacy of tDCS as a treatment for depression
Detailed Description:
Transcranial direct current stimulation tDCS applies a weak direct current across the scalp that can produce sub-threshold changes in the excitability of targeted cortical regions in a polarity-specific manner This technique has been used in humans to alter motor and visual cortex excitability during stimulation and for a period after the stimulation has ceased It has therefore been suggested as a possible treatment for depression Lippold Redfearn 1964 Nitsche 2002 Studies have been launched recently to examine the effect of tDCS in depressed subjects and a sham-controlled pilot study in USA in press has reported promising antidepressant effects with tDCS
We wish to examine this in an investigation of 20 subjects and hypothesise that tDCS will have an antidepressant effect and produce no neuropsychological impairment Subjects will receive anodal DC stimulation or sham stimulation over the left prefrontal cortex in a double-blind placebo-controlled design over 5 days and then have daily stimulation up to a maximum of 10 active sessions in total Outcomes will be formally evaluated by depression rating scales and neuropsychological tests
We wish to examine this in an investigation of 20 subjects and hypothesise that tDCS will have an antidepressant effect and produce no neuropsychological impairment Subjects will receive anodal DC stimulation or sham stimulation over the left prefrontal cortex in a double-blind placebo-controlled design over 5 days and then have daily stimulation up to a maximum of 10 active sessions in total Outcomes will be formally evaluated by depression rating scales and neuropsychological tests
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None