Ignite Creation Date:
2024-05-06 @ 9:34 AM
Last Modification Date:
2024-10-26 @ 12:16 PM
Study NCT ID:
NCT03013296
Status:
COMPLETED
Last Update Posted:
2019-06-04
First Post:
2017-01-03
Brief Title:
Delinieation of GIPs Effects During a Meal in Humans Using GIP Receptor Antagonisation GA-4
Sponsor:
University Hospital Gentofte Copenhagen
Organization:
University Hospital Gentofte Copenhagen
Study Overview
Official Title:
Delinieation of GIPs Effects During a Meal in Humans Using GIP Receptor Antagonisation GA-4
Status:
COMPLETED
Status Verified Date:
2019-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Delinieation of GIPs effects during a meal in humans using GIP receptor antagonisation
Detailed Description:
Aim To evaluate the role of GIPR signalling in postprandial physiology including lipid bone and glucose homeostasis using a naturally occurring GIP fragment which antagonises the GIPR
Twelve healthy men age 18-70 years BMI 19-27 kgm2 with normal kidney and liver parameters and haemoglobin levels and no first-degree relatives with type 2 diabetes will be included in a randomised double-blinded placebo-controlled cross-over study Study consists of four study days with concomitant infusions of A GIP-A B GLP-1 receptor antagonist Exendin9-39 C GIP-A Exendin9-39 or D saline placebo
Twelve healthy men age 18-70 years BMI 19-27 kgm2 with normal kidney and liver parameters and haemoglobin levels and no first-degree relatives with type 2 diabetes will be included in a randomised double-blinded placebo-controlled cross-over study Study consists of four study days with concomitant infusions of A GIP-A B GLP-1 receptor antagonist Exendin9-39 C GIP-A Exendin9-39 or D saline placebo
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None