Ignite Creation Date:
2024-05-05 @ 10:23 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005443
Status:
COMPLETED
Last Update Posted:
2016-02-18
First Post:
2000-05-25
Brief Title:
Race Class and Gender--Studies of Health Effects
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2000-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To improve understanding of three important and intertwined social determinants of health social class raceethnicity and gender
Detailed Description:
DESIGN NARRATIVE
The first component of the study investigated associations among discrimination blood pressure and cardiovascular risk factors and used data from Exam IV 1992-1993 of CARDIA a multi-site longitudinal study of cardiovascular risk factors among Black and white men and women Analyses examined the association between blood pressure and discrimination based on raceethnicity gender social class sexual orientation and religion and took into account response to unfair treatment To assess for effect modification separate analyses were performed for the eight strata defined by the sampling strategy Blackwhite x malefemale x equal to or less than high schoolmore than high school Additional multivariate analyses examined whether within the four gendereducation strata discrimination contributed to Blackwhite differences in blood pressure adjusting for relevant covariates Other analyses explored the relationship between discrimination response to unfair treatment and other possible cardiovascular risk factors including hostility body fat distribution lipid fractions blood glucose skin color substance use tobacco alcohol and illegal drugs and body self-image
The second component concerned appropriate measures of social class for studies of womens health It used data on 718 women who participated in Examination II of the Kaiser Permanente Women Twins Study 1989-1990 Socioeconomic information existed on adult individual and household class which took into account the individual class position of both the respondent and her partner or head-of-household if present childhood household class and class trajectory comparing childhood and adult household class Data on health characteristics included blood pressure body mass index waist-hip ratio lipoprotein fractions fasting and postload insulin and glucose serum concentrations self-assessed health status age at first completed pregnancy total number of childbirths duration of breast feeding physical activity and smoking status Analyses evaluated whether different magnitudes of class-based differences in these health characteristics were detected with these diverse measures of social class using multivariate techniques that corrected for the correlation of errors within twin pairs The effects of using these different class measures were also examined for analyses testing the hypothesis that social class was inversely related to risk of hypertension among women adjusting for relevant covariates
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
The first component of the study investigated associations among discrimination blood pressure and cardiovascular risk factors and used data from Exam IV 1992-1993 of CARDIA a multi-site longitudinal study of cardiovascular risk factors among Black and white men and women Analyses examined the association between blood pressure and discrimination based on raceethnicity gender social class sexual orientation and religion and took into account response to unfair treatment To assess for effect modification separate analyses were performed for the eight strata defined by the sampling strategy Blackwhite x malefemale x equal to or less than high schoolmore than high school Additional multivariate analyses examined whether within the four gendereducation strata discrimination contributed to Blackwhite differences in blood pressure adjusting for relevant covariates Other analyses explored the relationship between discrimination response to unfair treatment and other possible cardiovascular risk factors including hostility body fat distribution lipid fractions blood glucose skin color substance use tobacco alcohol and illegal drugs and body self-image
The second component concerned appropriate measures of social class for studies of womens health It used data on 718 women who participated in Examination II of the Kaiser Permanente Women Twins Study 1989-1990 Socioeconomic information existed on adult individual and household class which took into account the individual class position of both the respondent and her partner or head-of-household if present childhood household class and class trajectory comparing childhood and adult household class Data on health characteristics included blood pressure body mass index waist-hip ratio lipoprotein fractions fasting and postload insulin and glucose serum concentrations self-assessed health status age at first completed pregnancy total number of childbirths duration of breast feeding physical activity and smoking status Analyses evaluated whether different magnitudes of class-based differences in these health characteristics were detected with these diverse measures of social class using multivariate techniques that corrected for the correlation of errors within twin pairs The effects of using these different class measures were also examined for analyses testing the hypothesis that social class was inversely related to risk of hypertension among women adjusting for relevant covariates
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R29HL051151 | NIH | None | httpsreporternihgovquickSearchR29HL051151 |