Ignite Creation Date:
2024-05-05 @ 12:07 PM
Last Modification Date:
2024-10-26 @ 9:20 AM
Study NCT ID:
NCT00247533
Status:
UNKNOWN
Last Update Posted:
2009-02-09
First Post:
2005-10-31
Brief Title:
Cerebral Artery Stenosis Coronary Artery Disease and Arrhythmia
Sponsor:
Far Eastern Memorial Hospital
Organization:
Far Eastern Memorial Hospital
Study Overview
Official Title:
The Early Diagnosis and Prevention of Ischemic Stroke and Cognition Decline Associated With Coronary Artery Disease Combined With Cerebral Artery Stenosis or Arrhythmia by 24-Hour Simultaneous Recorder of Electrocardiograph and Electroencephalography
Status:
UNKNOWN
Status Verified Date:
2005-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
There are many reports about the association of coronary artery disease CAD and cerebral artery stenosis CAS which had been proved to induce stroke and cognition decline after the revascularization including coronary bypass surgery CABG or percutaneous coronary intervention Perfusion defect on nuclear brain scan is also noted to correlate with these neurological complications On the other hand the perioperative arrhythmia and following cerebral embolism was also attributed to be one factor inducing such neurological hazards
In the patients with coexistent CAD and CAS 1st group and also the patients scheduled for CABG or percutaneous coronary intervention PCI 2nd group we the researchers at Far Eastern Memorial Hospital attempted to integrate all the parameters mention above including angiography of coronary and cerebral system quantitative analysis of nuclear brain scan biochemical profile and signals of a new ambulatory device which could record the electrocardiograph ECG and electroencephalograph EEG simultaneously in order to define the correlation between them A chorological relation between EEG signals and ECG signals is our first target to be worked out Thereafter we hope to establish a regression model of all involved parameters according to the relation Such a model we believe is essential not only to explain the post-CABG neurological complications but to prevent them
Furthermore for the undetermined ischemic stroke patients who had no obvious culprit artery or embolism source the paroxysmal arrhythmia had long been regarded as the cause Whether a paroxysmal atrial fibrillation which had not been disclosed by routine ECG could induce most of such a stroke is still not known With this new ambulatory device which could record the electrocardiograph ECG and electroencephalograph EEG simultaneously we want to answer the question
In the patients with coexistent CAD and CAS 1st group and also the patients scheduled for CABG or percutaneous coronary intervention PCI 2nd group we the researchers at Far Eastern Memorial Hospital attempted to integrate all the parameters mention above including angiography of coronary and cerebral system quantitative analysis of nuclear brain scan biochemical profile and signals of a new ambulatory device which could record the electrocardiograph ECG and electroencephalograph EEG simultaneously in order to define the correlation between them A chorological relation between EEG signals and ECG signals is our first target to be worked out Thereafter we hope to establish a regression model of all involved parameters according to the relation Such a model we believe is essential not only to explain the post-CABG neurological complications but to prevent them
Furthermore for the undetermined ischemic stroke patients who had no obvious culprit artery or embolism source the paroxysmal arrhythmia had long been regarded as the cause Whether a paroxysmal atrial fibrillation which had not been disclosed by routine ECG could induce most of such a stroke is still not known With this new ambulatory device which could record the electrocardiograph ECG and electroencephalograph EEG simultaneously we want to answer the question
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None