Ignite Creation Date:
2024-05-06 @ 9:19 AM
Last Modification Date:
2024-10-26 @ 12:13 PM
Study NCT ID:
NCT02956148
Status:
COMPLETED
Last Update Posted:
2019-10-10
First Post:
2016-03-11
Brief Title:
Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntingtons Disease Gene Expansion Carriers
Sponsor:
CHDI Foundation Inc
Organization:
CHDI Foundation Inc
Study Overview
Official Title:
Follow-up Measurement of Brain Phosphodiesterase 10 A PDE10A Enzyme Levels in Huntingtons Disease Gene Expansion Carriers 18 to 28 Months After Initial Positron Emission Tomography PET Measurement in CHDIKI1201PET-HD-PDE10A NCT02061722
Status:
COMPLETED
Status Verified Date:
2019-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LONGPDE10
Brief Summary:
The aim of this study is to measure longitudinally the availability of the PDE10A enzyme in HDGECs using the radioligand 18FMNI-659 The study will be a follow-up examining HDGECs from the CHDIKI1201PET-HD-PDE10A NCT02061722 study from 18 to 28 months after the initial PET measurement
Detailed Description:
The HDGECs will perform 2 study visits Visit 1 screening and Visit 2 PET analysis utilizing the radioligand 18FMNI-659 There will also be 2 telephone follow ups one after Visit 1 telephone follow-up after screening and one after Visit 2 telephone follow-up after PET Study visits and telephone follow-ups will take place during a maximum of 97 days
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None