Ignite Creation Date:
2024-05-06 @ 9:17 AM
Last Modification Date:
2024-10-26 @ 12:12 PM
Study NCT ID:
NCT02952066
Status:
WITHDRAWN
Last Update Posted:
2021-06-14
First Post:
2016-10-29
Brief Title:
Expressions of TRPV1 in Airway of Asthmatics
Sponsor:
Lu Yuan Lee
Organization:
University of Kentucky
Study Overview
Official Title:
Expressions of TRPV1 in Airway of Asthmatics
Status:
WITHDRAWN
Status Verified Date:
2021-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Prior to any participant enrollment the PI opted to not move forward with the study
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
TRPV1
Brief Summary:
The purpose of this study is to measure the density of a temperature-sensitive protein named TRPV1 in the airway mucosa tissue of both non-asthmatic and moderate to severe persistent asthmatic patients This study may generate information for developing new therapeutic strategy
Detailed Description:
The research procedure will be conducted at University of Kentucky AB Chandler Hospital dedicated bronchoscopy suite located on third floor of Pavilion H module room 2 and will be performed only once as part of a standard of care bronchoscopy procedure scheduled by the participants pulmonary physician This entire study biopsy will add 10 minutes or less Following the biopsy and after being discharged from the hospital the participants study participation will end
Bronchial Biopsy The investigator will collect five lung bronchial specimens 1-2 cubic millimeters each from three zones of the participants airway which will be individually coded and stored for the computer image analysis of TRPV1 in the investigators laboratory Following analysis the samples will be destroyed The results of the analysis cannot be used for determining a clinical diagnosis Therefore the investigator will not provide any findings to either the participant or their physician
Participants will not get any personal benefit from taking part in this study Their willingness to take part in this research study may in the future help doctors better understand andor treat patients with asthma
There will be no cost to the participant for having the bronchial biopsy performed
Participants will not receive any rewards or payment for taking part in the study
Bronchial Biopsy The investigator will collect five lung bronchial specimens 1-2 cubic millimeters each from three zones of the participants airway which will be individually coded and stored for the computer image analysis of TRPV1 in the investigators laboratory Following analysis the samples will be destroyed The results of the analysis cannot be used for determining a clinical diagnosis Therefore the investigator will not provide any findings to either the participant or their physician
Participants will not get any personal benefit from taking part in this study Their willingness to take part in this research study may in the future help doctors better understand andor treat patients with asthma
There will be no cost to the participant for having the bronchial biopsy performed
Participants will not receive any rewards or payment for taking part in the study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| U01AI123832 | NIH | None | httpsreporternihgovquickSearchU01AI123832 |