Ignite Creation Date:
2024-05-06 @ 9:15 AM
Last Modification Date:
2024-10-26 @ 12:12 PM
Study NCT ID:
NCT02943031
Status:
UNKNOWN
Last Update Posted:
2019-10-18
First Post:
2016-10-20
Brief Title:
The Effect of Individualized Precision Therapy Programs in Patients With BTC
Sponsor:
RenJi Hospital
Organization:
RenJi Hospital
Study Overview
Official Title:
The Effect of Individualized Precision Therapy Programs in Patients With Biliary Tract Cancer
Status:
UNKNOWN
Status Verified Date:
2019-10
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This is a prospective cohort study Patients who meet the inclusion criteria will be enrolled in this study The samples of biliary tract tumors will be collected Genome sequencing mini-PDX and PDX will be performed according to the requirement of individualized precision therapy programs Suitable drugs will be chose according to drug screening results OS and PFS will be compared with traditional chemotherapy to evaluate the effect of individualized precision therapy programs
Detailed Description:
In this prospective cohort study patients who are eligible for inclusion criteria will enroll in the study After bile duct tumor samples were collected whole genome sequencing drug screening including Mini-PDX and PDX will conduct Suitable drugs will be decided according to the different genomics classification and then to develop individualized precise treatment programs
The investigators hope to achieve the following objectives
① Through the establishment of Individualized Precision Therapy Programs to improve the overall survival of bile duct malignancy BTC
② To study the molecular typing of the prognosis of biliary malignancy
③ To construct a database of BTC gene bank as well as for drug screening information
The investigators hope to achieve the following objectives
① Through the establishment of Individualized Precision Therapy Programs to improve the overall survival of bile duct malignancy BTC
② To study the molecular typing of the prognosis of biliary malignancy
③ To construct a database of BTC gene bank as well as for drug screening information
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
None