Ignite Creation Date:
2024-05-05 @ 10:23 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005455
Status:
COMPLETED
Last Update Posted:
2016-07-15
First Post:
2000-05-25
Brief Title:
Chagas Disease as an Undiagnosed Type of Cardiomyopathy in the United States
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2001-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
A detailed review was made of data pertinent to the occurrence of chronic Chagas disease in the United States
Detailed Description:
BACKGROUND
In Latin America 16 to 18 million individuals are thought to have Chagas disease and 90 million are considered to be at risk of infection In the United States the occurrence of Chagas disease is virtually limited to individuals who have resided in Latin America where they acquired the infection and then migrated to this country
DESIGN NARRATIVE
Data on the prevalence of positive serologic reactions for Trypanosoma cruzi a protozoan causing Chagas cardiomyopathy serve for calculating that a total of up to 74000 Latin Americans residing in the United States have the chronic form of chagasic cardiomyopathy The vast majority of these individuals are either undiagnosed or misdiagnosed as having idiopathic dilated cardiomyopathy or coronary artery disease Vector transmission of T cruzi infection is very unlikely to occur in the United States because of variations in biological behavior of local species of insect vectors and because of changes in human living conditions Transfusion of blood from infected but asymptomatic individuals is considered the most important mechanism of transmission of this disorder in the United States
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
In Latin America 16 to 18 million individuals are thought to have Chagas disease and 90 million are considered to be at risk of infection In the United States the occurrence of Chagas disease is virtually limited to individuals who have resided in Latin America where they acquired the infection and then migrated to this country
DESIGN NARRATIVE
Data on the prevalence of positive serologic reactions for Trypanosoma cruzi a protozoan causing Chagas cardiomyopathy serve for calculating that a total of up to 74000 Latin Americans residing in the United States have the chronic form of chagasic cardiomyopathy The vast majority of these individuals are either undiagnosed or misdiagnosed as having idiopathic dilated cardiomyopathy or coronary artery disease Vector transmission of T cruzi infection is very unlikely to occur in the United States because of variations in biological behavior of local species of insect vectors and because of changes in human living conditions Transfusion of blood from infected but asymptomatic individuals is considered the most important mechanism of transmission of this disorder in the United States
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| Z01HL005264 | NIH | None | httpsreporternihgovquickSearchZ01HL005264 |