Ignite Creation Date:
2025-12-24 @ 3:59 PM
Ignite Modification Date:
2026-02-04 @ 11:01 PM
Study NCT ID:
NCT02200692
Status:
COMPLETED
Last Update Posted:
2021-06-16
First Post:
2014-06-27
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Allergic Transfusion Reactions in Plasma Transfusion
Sponsor:
Haukeland University Hospital
Organization:
Study Overview
Official Title:
Risk Factors for Allergic Transfusion Reactions in Patients Receiving Plasma Transfusion
Status:
COMPLETED
Status Verified Date:
2021-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Allergic transfusion reactions are a common complication of transfusion by blood components containing plasma. This study aims to investigate passive transfer of Immunoglobin E antibodies as a risk factor of allergic reactions to plasma transfusion by use of Solvent Detergent plasma.
Detailed Description:
Prospective observation study, aiming to measure transfer of Immunoglobin E antibodies and other factors associated with allergic complications in patients receiving plasma transfusion. Samples from patients and plasma units will be investigated. Samples frozen until investigation. To assess biological relevance of findings, additional analysis of basophil reactivity will be performed and information on clinical allergy collected by use of a questionaire .
In-patients will be recruited if receiving plasma transfusion during surgery or if an allergic transfusion complication occurs.
In-patients will be recruited if receiving plasma transfusion during surgery or if an allergic transfusion complication occurs.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| REK 2014/607 | OTHER | REC West 2014/607 | View |