Viewing Study NCT02897791



Ignite Creation Date: 2024-05-06 @ 9:05 AM
Last Modification Date: 2024-10-26 @ 12:09 PM
Study NCT ID: NCT02897791
Status: COMPLETED
Last Update Posted: 2017-11-22
First Post: 2016-07-27

Brief Title: Main Idea Perception of Written Stories and in Pictures Among Impaired Right Hemisphere Patients
Sponsor: Sheba Medical Center
Organization: Sheba Medical Center

Study Overview

Official Title: Main Idea Perception of Written Stories and in Pictures Among Impaired Right Hemisphere Patients
Status: COMPLETED
Status Verified Date: 2017-11
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: stroke
Brief Summary: Main idea perception of written stories and in pictures among impaired right hemisphere patients Abstract The right hemisphere is considered to complement the language processing abilities of the opposite hemisphere it is responsible for the processing of secondary and unusual characteristics of linguistic stimulates This processing enables among other functions the comprehension of metaphors and humor Additionally it enables the execution of inferring from spoken and written discourse Studies which deal with common impairments among right-hemisphere-damaged RHD individuals found that inference processing of written stories and narrative sequences presented in pictures was impaired This impairment could damage the ability to create global coherence which is an important component of central theme comprehension of different types of narrative Another important component is superstructures schemas which aid creating remembering and producing the main ideas of spoken and written discourse Other studies consider impairment in creating global coherence or Theory of Mind impairment as the source of central theme comprehension impairment among RHD individuals

Discourse is an integral part of interpersonal communication and of proper social conduct The themes chosen for conversation reflect the functional role of discourse from semantic and pragmatic points of view

The aim of the current study is to deepen the current knowledge concerning central theme comprehension among RHD individuals following cerebrovascular accident CVA in two genres of written discourse classic stories and stories with a twist and in situations represented by single pictures Unlike written stories the extraction of the central theme out of a single picture requires focusing on a single situation and relying on non-linguistic visual information Differences concerning central theme comprehension in the different discourse genres and in the pictures might be able to assist in selecting diagnostic and therapeutic tools designed to work on high cognitive-linguistic abilities which are usually impaired among RHD individuals In later stage these tools are meant to help improving RHD individuals spontaneous narrative skills

The study will include 20 RHD adults following CVA and 20 healthy adults without any known damage to the right hemisphere The two groups will be matched concerning sex age educational level and socio-economic status The subjects will perform the study tests during three sessions 60 minutes each The screening tests will include language diagnosis - Western Aphasia Battery WAB and reading test no 37 included in the Psycholinguistic Assessments of Language Processing in Aphasias battery PALPA Patients diagnosed with aphasia will be excluded from research The research tests will include central theme comprehension test in stories and pictures including classic stories stories with a twist and pictures of different situations each will be accompanied by a multiple-choice question concerning the central theme sub- exanimations taken from Frigbi battery designed to evaluate memory and phonological memory capacity Ravens Progressive Colored Matrices test designed to evaluate pre-morbid abilities non-linguistic Theory of Mind TOM evaluation test and tests designed to evaluate central coherence impairment Navon Figures test for evaluation of global visual perception impairment and Rey-Osterrieth Complex Figure Test RCFT - Recall Form test for evaluation of visual-perceptive organizational ability and non-verbal memory The performances of the two groups will be compared in each test using statistical tests In addition the interaction between all variables will be measured
Detailed Description: None

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None