Ignite Creation Date:
2024-05-06 @ 9:05 AM
Last Modification Date:
2024-10-26 @ 12:09 PM
Study NCT ID:
NCT02894099
Status:
UNKNOWN
Last Update Posted:
2016-09-09
First Post:
2016-07-26
Brief Title:
Cardiovascular Risk in Sedentary Elderly During Prolonged Sitting Time Versus Intermittent Sitting Time
Sponsor:
University of Sao Paulo
Organization:
University of Sao Paulo
Study Overview
Official Title:
Blood Glucose Insulin Response and Inflammatory Markers in Sedentary Elderly During Prolonged Sitting Time Versus Intermittent Sitting Time
Status:
UNKNOWN
Status Verified Date:
2016-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In adults the sedentary behavior was related to cardiovascular risk markers regardless of the level of physical activity PA However the interruption of prolonged sedentary time has shown positive results even when performed in breaks of low intensity and short duration of activity The aim of this study is to analyze the influence of a sedentary uninterrupted period as well as different forms of breaks in sedentary time for the glycemic insulin and inflammatory markers responses in older adults This is a controlled clinical trial to be conducted in older 65 years and sedentary 150 min week of moderate to vigorous physical activity people Those with BMI to 3500 kg m2 diabetic on medication for glycemic control or with absolute or relative contraindications to PA practice will not be included Participants will undergo four phases of intervention separated by an interval of 7 days 1 Prolonged Sitting TimePST in which older people will stay for 5 hours seated 2 Prolonged sitting with PA of light intensity and short duration LiSd time sitting is interrupted for PA bouts of 50-60 of the Heart Rate HRmax 3 Prolonged sitting with PA of moderate intensity and short duration MiSd time sitting will be interrupted for PA bouts of 65-75 predicted HR max 4 Prolonged sitting with PA of moderate intensity and long duration MiLd time sitting will be interrupted with PA bouts of 65-75 of HRmax PA bouts will be performed by walking into a hallway every 20 minutes of sitting time and will last 2 minutes except in MiLd phase 10 minute breaks every 75 minutes To evaluate the effects of different PA interruptions in plasma glucose serum insulin and inflammatory markers blood samples will be collected serially -30min Baseline and 30min 1h 2h 3h 4h and 5h after a standardized meal It is expect that interruption of sedentary time even with breaks of short duration and light intensity can bring benefits to cardiovascular risk markers even in the elderly
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None