Ignite Creation Date:
2024-05-05 @ 12:05 PM
Last Modification Date:
2024-10-26 @ 9:19 AM
Study NCT ID:
NCT00230412
Status:
UNKNOWN
Last Update Posted:
2010-02-02
First Post:
2005-09-28
Brief Title:
Study of Heat Shock Proteins as Prognostic Factor of Acute Renal Failure in Children HSP-Study
Sponsor:
University of Munich Childrens Clinic
Organization:
University of Munich Childrens Clinic
Study Overview
Official Title:
Study of Heat Shock Proteins as Prognostic Factor of Acute Renal Failure in Children HSP-Study
Status:
UNKNOWN
Status Verified Date:
2010-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
HSP
Brief Summary:
The purpose of the investigators study is to determine whether the production of heat shock proteins has an effect on the development and the outcome of acute renal failure in children
Detailed Description:
A prognostic factor for the development of acute renal failure ANR in children would be very valuable for therapy regulation So-called chaperones out of the family of heat shock proteins HSP are promising candidates which are involved in the development of ANR as well This could be a starting point for the development of new therapeutic approaches
ANR occurs in up to 50 percent of all critical ill patients and has a high rate of morbidity and mortality despite advances in symptomatic therapy Following severe sepsis septic shock or other shocks combined with multiple organ failure the ANR is an autonomous prognosis worsening factor
Should the results of our study show a correlation between the production of HSP and the outcome of children with ANR further studies would be required to examine the pathophysiological relevance of HSP in ANR We would then be able to determine a high risk population for ANR A modulation of ANR therapy might be a result of further studies
ANR occurs in up to 50 percent of all critical ill patients and has a high rate of morbidity and mortality despite advances in symptomatic therapy Following severe sepsis septic shock or other shocks combined with multiple organ failure the ANR is an autonomous prognosis worsening factor
Should the results of our study show a correlation between the production of HSP and the outcome of children with ANR further studies would be required to examine the pathophysiological relevance of HSP in ANR We would then be able to determine a high risk population for ANR A modulation of ANR therapy might be a result of further studies
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| Projektnummer 233-05 | None | None | None |