Ignite Creation Date:
2024-05-06 @ 9:03 AM
Last Modification Date:
2024-10-26 @ 12:09 PM
Study NCT ID:
NCT02896881
Status:
RECRUITING
Last Update Posted:
2024-07-11
First Post:
2016-09-07
Brief Title:
Interest of New MRI Sequences After Embolization of Brain Arteriovenous Malformations
Sponsor:
Fondation Ophtalmologique Adolphe de Rothschild
Organization:
Fondation Ophtalmologique Adolphe de Rothschild
Study Overview
Official Title:
Interest of New MRI Sequences After Embolization of Brain Arteriovenous Malformations MAV-IRM
Status:
RECRUITING
Status Verified Date:
2024-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MAV-IRM
Brief Summary:
In previous studies exploring specific sequences of MRI susceptibility weighted imaging SWI and arterial spin labeling ASL the investigators have shown the great sensibility of these MRI sequences to detect arteriovenous shunts compared to angiography imaging static or dynamic This prospective study aims to compare multisequence MRI to brain arteriography imaging in patients undergoing brain arteriovenous malformations embolization
Detailed Description:
Cerebral arteriovenous malformations are treated to eliminate the potential risk of haemorrhage There are three possible treatment modalities surgery radiosurgery or embolisation Complete exclusion of the arteriovenous malformation is a prerequisite for confirming that there is no residual risk of haemorrhage After treatment arteriography is the gold standard for confirming this exclusion The absence of early opacification of the venous drainage is considered a sign of cure
Several arteriographic aspects are possible after treatment by embolisation
Arteriography may be strictly normal no abnormalities
The persistence of early venous opacification presence of arterialised blood indicates the persistence of a residual AVM
Other vascular anomalies without early venous drainage may be present dysplastic vessels irregular shape corkscrew appearance capillary blush in the embolisation bed hyperaemia other slow flow slow filling or widening of afferent arteries
Our previous studies exploring the use of specific MRI sequences in magnetic susceptibility SWI arterial spin labelling ASL and angiography static or dynamic sequences have enabled us to demonstrate the very high sensitivity of these sequences for detecting an arteriovenous shunt whether native when the AVM is discovered or residual after treatment We would like to carry out a prospective study to compare cerebral arteriography and MRI multi-sequence in patients treated by embolisation for cerebral arteriovenous malformation
Several arteriographic aspects are possible after treatment by embolisation
Arteriography may be strictly normal no abnormalities
The persistence of early venous opacification presence of arterialised blood indicates the persistence of a residual AVM
Other vascular anomalies without early venous drainage may be present dysplastic vessels irregular shape corkscrew appearance capillary blush in the embolisation bed hyperaemia other slow flow slow filling or widening of afferent arteries
Our previous studies exploring the use of specific MRI sequences in magnetic susceptibility SWI arterial spin labelling ASL and angiography static or dynamic sequences have enabled us to demonstrate the very high sensitivity of these sequences for detecting an arteriovenous shunt whether native when the AVM is discovered or residual after treatment We would like to carry out a prospective study to compare cerebral arteriography and MRI multi-sequence in patients treated by embolisation for cerebral arteriovenous malformation
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None