Ignite Creation Date:
2024-05-06 @ 9:01 AM
Last Modification Date:
2024-10-26 @ 12:09 PM
Study NCT ID:
NCT02886793
Status:
COMPLETED
Last Update Posted:
2019-09-18
First Post:
2016-08-29
Brief Title:
Cell Proliferation in Pulmonary Hypertension FDG-PET Comparison Between Patients and Healthy Subjects
Sponsor:
Joan Albert Barbera Mir
Organization:
Hospital Clinic of Barcelona
Study Overview
Official Title:
Cell Proliferation in Pulmonary Hypertension FDG-PET Comparison Between Patients and Healthy Subjects
Status:
COMPLETED
Status Verified Date:
2019-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PROCLAIM
Brief Summary:
Pulmonary arterial hypertension PAH and chronic thromboembolic pulmonary hypertension CTEPH are serious diseases with poor prognosis despite recent advances Currently pulmonary hypertension PH is considered a cell proliferative disorder which has not been adequately characterized due to the lack of markers A better understanding of the mechanisms that regulate this proliferative disorder will allow the identification of new therapeutic targets for HP
The objective of the project is to identify cell proliferative processes in severe forms of PH Patients with PAH n20 CTEPH n20 and healthy controls n20 will undergo characterization of microRNAs miRNAs contained within circulating microparticles MPs analysis and mitochondrial functionality and FDG-PET to compare cell metabolism in the lungs and the right ventricle between patients and controls
The objective of the project is to identify cell proliferative processes in severe forms of PH Patients with PAH n20 CTEPH n20 and healthy controls n20 will undergo characterization of microRNAs miRNAs contained within circulating microparticles MPs analysis and mitochondrial functionality and FDG-PET to compare cell metabolism in the lungs and the right ventricle between patients and controls
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None