Ignite Creation Date:
2024-05-06 @ 9:00 AM
Last Modification Date:
2024-10-26 @ 12:08 PM
Study NCT ID:
NCT02875990
Status:
UNKNOWN
Last Update Posted:
2016-08-23
First Post:
2016-08-12
Brief Title:
Characterization of Immunosuppressive Signing of Cervical Cancer
Sponsor:
Assistance Publique Hopitaux De Marseille
Organization:
Assistance Publique Hopitaux De Marseille
Study Overview
Official Title:
Characterization of Immunosuppressive Signing of Cervical Cancer
Status:
UNKNOWN
Status Verified Date:
2016-08
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Xac03
Brief Summary:
Infection with Human Papillomavirus high-risk Human HR-HPV is the main factor of risk of cancer of the cervix Recent studies show that cancers linked to infection with HR-HPV are associated with immunosuppression and lack of T cell response Such mechanisms would promote progression to cancer and progression of it Various factors such as an increase of regulatory T cells the presence of myeloid cells and suppressor of defects in the signaling pathway Toll Like Receptor TLR may have a key role in these immunosuppression mechanisms At this stage of knowledge a better characterization of local and systemic immunosuppressive signing of cervical cancer is needed The results should have a significant medical impact for the identification of new prognostic markers and new therapeutic targets for the treatment of patients with cervical cancer
The aim of this research project is to define the signing of immunosuppressive cancer cervix and analyze the different mechanisms involved in this immunosuppression
The aim of this research project is to define the signing of immunosuppressive cancer cervix and analyze the different mechanisms involved in this immunosuppression
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2015-A00699-40 | REGISTRY | IDRCB | None |