Ignite Creation Date:
2024-05-05 @ 12:05 PM
Last Modification Date:
2024-10-26 @ 9:19 AM
Study NCT ID:
NCT00231205
Status:
UNKNOWN
Last Update Posted:
2005-10-04
First Post:
2005-09-30
Brief Title:
TDI Preejection Velocities and Myocardial Viability
Sponsor:
Charles University Czech Republic
Organization:
Charles University Czech Republic
Study Overview
Official Title:
TDI-Derived Myocardial Preejection Velocities in Patients With Chronic Ischemic Left Ventricular Dysfunction Undergoing Surgical Revascularization
Status:
UNKNOWN
Status Verified Date:
2005-09
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of the study is to test accuracy of positive preejection velocity to predict left ventricular remodeling and long-term prognosis after revascularization in 200 patients with chronically dysfunctional myocardium Patients will be followed for 3 years
Our hypothesis is that tissue-Doppler-derived analysis of positive preejection velocity allows to select optimal responders to revascularization it means individuals with the greatest benefit in terms of LV remodeling and long-term prognosis
Our hypothesis is that tissue-Doppler-derived analysis of positive preejection velocity allows to select optimal responders to revascularization it means individuals with the greatest benefit in terms of LV remodeling and long-term prognosis
Detailed Description:
The objective of the project is to study clinical and prognostic value of new echocardiographic technique so called positive preejection velocity VIC in patients with chronic ischemic left ventricular LV dysfunction indicated for revascularization Pilot studies has shown high accuracy of pulsed Tissue Doppler imaging TDI-derived resting pattern of VIC to detect viable myocardium in patients with both acute myocardial infarction and chronically dysfunctional myocardium The aim of the project is to test accuracy of VIC to predict LV remodeling and long-term prognosis after revascularization in patients with chronically dysfunctional myocardium Study population will consist of two groups of patients with stable ischemic LV dysfunction group A- patients indicated for revascularization n200 group B- matched control group treated conservatively case-control design n100 All patients will be followed for 3 years Endpoints include 1 LV remodeling at 6 and 24 months and 2 MACE at 6 12 and 36 months follow-up Our hypothesis is that TDI-derived analysis of VIC allows to select optimal responders to revascularization it means individuals with the greatest benefit in terms of LV remodeling and long-term prognosis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None