Ignite Creation Date:
2024-05-06 @ 8:56 AM
Last Modification Date:
2024-10-26 @ 12:08 PM
Study NCT ID:
NCT02869464
Status:
UNKNOWN
Last Update Posted:
2016-08-17
First Post:
2014-12-01
Brief Title:
UVA Brain and Aortic Aneurysm Study
Sponsor:
University of Virginia
Organization:
University of Virginia
Study Overview
Official Title:
The University of Virginia Brain and Aortic Aneurysm Study
Status:
UNKNOWN
Status Verified Date:
2016-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BAAS
Brief Summary:
The purpose of this study is to examine the percentage of patients who present with abdominal aortic aneurysms AAA will also have intracranial aneurysms IA and conversely to examine the percentage of patients who present with intracranial aneurysms will also have abdominal aortic aneurysms
Detailed Description:
The investigators have previously generated estimates for cost effectiveness of each arm of this reciprocal screening protocol based on literature dervied estimates of coprevalence and other key factors in a decision tree model to compare costs and outcomes They measured expected outcomes using quality-adjusted life years QALY and the incremental cost-effectiveness ratios ICER The current study will involve establishment of the true co-prevalence and recalculation of the ICERs and QALYs Based on their literature derived models we previously found an ICER of 3401QALY for AAA screening in IA patients and an ICER of 640191QALY for IA screening in AAA patients Both of these are well below the societal accepted threshold of 60000QALY However both models were sensitive to co-prevalence In the current study the investigators will therefore determine the actual cost-effectiveness of performing additional radiographic procedures and genetic counseling The investigators will also bank DNA and RNA for future research
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None