Ignite Creation Date:
2024-05-06 @ 8:49 AM
Last Modification Date:
2024-10-26 @ 12:05 PM
Study NCT ID:
NCT02820649
Status:
COMPLETED
Last Update Posted:
2016-07-01
First Post:
2016-06-23
Brief Title:
Protective Effects of Exercise Training
Sponsor:
Institut de Recherche Biomedicale des Armees
Organization:
Institut de Recherche Biomedicale des Armees
Study Overview
Official Title:
Protective Effects of Exercise Training on Endothelial Dysfunction Induced by Total Sleep Deprivation in Healthy Subjects
Status:
COMPLETED
Status Verified Date:
2016-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SOMEX
Brief Summary:
Rationale Sleep loss is a risk factor for cardiovascular events mediated through endothelial dysfunction
Objective To determine if 7 weeks of exercise training can limit cardiovascular dysfunction induced by total sleep deprivation TSD in healthy young men
Methods 16 subjects will be examined during 40-h TSD both before and after 7 weeks of interval exercise training Vasodilatation induced by ACh insulin and heat 42C as well as pulse wave velocity PWV blood pressure and heart rate HR will be assessed at baseline during TSD and after one night of sleep recovery Biomarkers of endothelial activation inflammation and hormones will bemeasured from morning blood samples at 0700
Objective To determine if 7 weeks of exercise training can limit cardiovascular dysfunction induced by total sleep deprivation TSD in healthy young men
Methods 16 subjects will be examined during 40-h TSD both before and after 7 weeks of interval exercise training Vasodilatation induced by ACh insulin and heat 42C as well as pulse wave velocity PWV blood pressure and heart rate HR will be assessed at baseline during TSD and after one night of sleep recovery Biomarkers of endothelial activation inflammation and hormones will bemeasured from morning blood samples at 0700
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2014_A01103-44 | OTHER | IDRCB ANSM | None |