Ignite Creation Date:
2024-05-06 @ 8:48 AM
Last Modification Date:
2024-10-26 @ 12:05 PM
Study NCT ID:
NCT02823782
Status:
COMPLETED
Last Update Posted:
2016-07-06
First Post:
2016-06-09
Brief Title:
MRI Investigations in Attention Deficit Hyperactivity Disorder ADHD and High Potential HP Children for a Better Therapeutic Approach
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
MRI Investigations in Attention Deficit Hyperactivity Disorder ADHD and High Potential HP Children for a Better Therapeutic Approach
Status:
COMPLETED
Status Verified Date:
2016-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
HP
Brief Summary:
Impulsivity andor hyperactivity in children has become one of the main clinical symptom for consultation among the most frequent in general or pediatric medicine Among the different clinical forms of instability ADHD appears to be an especially disabling condition for the development of the child both in psychomotor cognitive emotional and relational aspects Further a significant link between ADHD children and some children with High Potential HP is observed HP children show overall ahead cognitive developments compared to children with the same age In these children as well as in children with ADHD an attention vulnerability psychomotor deficits are noted as well as emotional and relational deficits that significantly contrasted with some of their cognitive skills Regarding the HP the hypothesis is that children with significantly heterogeneous results Complex to the Wechsler IV scales are affected by this shift and hence by the difficulty of a differential diagnosis with ADHD unlike those whose intelligence quotient IQ results that are more homogeneous Laminar
The goal of this work was to study a population of 80 children aged from 8 to 12 years 20 subjects per group to evaluate the functional and structural brain development by
Functional magnetic resonance imaging fMRI acquisitions with cognitive stimulations involving attention working memory and semantic processing and emotional stimulations
fMRI acquisitions at rest without activation
diffusion tensor magnetic resonance imaging DTI acquisitions
3D anatomic acquisitions Identification of developmental differences in certain cortical brain areas eg prefrontal vs parietal white matter fiber bundles or functional networks preferentially used by one or other of these groups will help to better understand this disease and to improve the differential diagnosis in order to implement a more appropriate and personalized management of the patients via new therapeutic strategies
The goal of this work was to study a population of 80 children aged from 8 to 12 years 20 subjects per group to evaluate the functional and structural brain development by
Functional magnetic resonance imaging fMRI acquisitions with cognitive stimulations involving attention working memory and semantic processing and emotional stimulations
fMRI acquisitions at rest without activation
diffusion tensor magnetic resonance imaging DTI acquisitions
3D anatomic acquisitions Identification of developmental differences in certain cortical brain areas eg prefrontal vs parietal white matter fiber bundles or functional networks preferentially used by one or other of these groups will help to better understand this disease and to improve the differential diagnosis in order to implement a more appropriate and personalized management of the patients via new therapeutic strategies
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None