Ignite Creation Date:
2024-05-06 @ 8:45 AM
Last Modification Date:
2024-10-26 @ 12:04 PM
Study NCT ID:
NCT02810262
Status:
UNKNOWN
Last Update Posted:
2019-04-02
First Post:
2016-06-20
Brief Title:
Association of Bone and Metabolic Parameters With Overall Survival in Patients With Bone Metastases From Adenocarcinoma Lung Cancer POUMOS
Sponsor:
Hospices Civils de Lyon
Organization:
Hospices Civils de Lyon
Study Overview
Official Title:
Association of Bone and Metabolic Parameters With Overall Survival in Patients With Bone Metastases From Adenocarcinoma Lung Cancer POUMOS
Status:
UNKNOWN
Status Verified Date:
2019-04
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
POUMOS
Brief Summary:
Mortality due to non small cell lung cancers is the first cause of cancer death in men around the world Lung adenocarcinoma regularly induces bone metastases responsible for high morbidity and impaired life quality Overall survival of these patients is poor Thus the investigators aimed to identify if some bone and metabolic parameters were associated with overall survival
Patients and Methods POUMOS is a prospective cohort of patients suffering from adenocarcinoma lung cancers with a first bone metastasis stage IV All patients have a bone biopsy with molecular status characterization of the tumor for EGFR KRAS BRAF and ALK Bone metastasis localizations are obtained by bone scintigraphy or FDG-PETCT Whole body composition is obtained by DEXA scan Hologic The investigators assessed also fasting blood levels of bone and metabolic biomarkers
Survival analyses will be performed using a proportional hazard regression model
Patients and Methods POUMOS is a prospective cohort of patients suffering from adenocarcinoma lung cancers with a first bone metastasis stage IV All patients have a bone biopsy with molecular status characterization of the tumor for EGFR KRAS BRAF and ALK Bone metastasis localizations are obtained by bone scintigraphy or FDG-PETCT Whole body composition is obtained by DEXA scan Hologic The investigators assessed also fasting blood levels of bone and metabolic biomarkers
Survival analyses will be performed using a proportional hazard regression model
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None