Ignite Creation Date:
2024-05-06 @ 8:44 AM
Last Modification Date:
2024-10-26 @ 12:04 PM
Study NCT ID:
NCT02809820
Status:
COMPLETED
Last Update Posted:
2022-03-31
First Post:
2016-06-20
Brief Title:
Effects of Beta-blockade on Platelet Aggregation in Acute Coronary Syndrome
Sponsor:
Federico II University
Organization:
Federico II University
Study Overview
Official Title:
Effects of Selective and Nonselective Beta-blockade on Platelet Aggregation in Patients With Acute Coronary Syndrome
Status:
COMPLETED
Status Verified Date:
2022-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
PLATE-BLOCK
Brief Summary:
The Investigators will test the hypothesis that nonselective beta-blockers would have a more pronounced effect on platelet aggregation than selective beta-blockers in patients with acute coronary syndrome treated with dual anti platelet therapy
Detailed Description:
In patients with acute coronary syndrome ACS beta-blockers are recommended for secondary prevention It is known that catecholamine levels can potentiate platelet reactivity and beta-blocking agents may also affect platelet aggregation This effect is mainly mediated by adrenergic receptors on platelets This suggests that nonselective beta-blockers would have a more pronounced effect on platelet aggregation than selective beta-blockers However little is known about the effect of beta-blockers on platelet aggregation in patients with cardiovascular disease and to date nothing is known in the setting of ACS
The aim of the present study is to evaluate the effect of selective and nonselective beta-blockers on platelet aggregation in ACS patients treated with dual anti platelet therapy
The aim of the present study is to evaluate the effect of selective and nonselective beta-blockers on platelet aggregation in ACS patients treated with dual anti platelet therapy
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None