Ignite Creation Date:
2024-05-06 @ 8:44 AM
Last Modification Date:
2024-10-26 @ 12:04 PM
Study NCT ID:
NCT02809378
Status:
COMPLETED
Last Update Posted:
2017-07-21
First Post:
2016-06-16
Brief Title:
The Effects of Anesthetic Techniques and Palonosetron Administration on the Incidence of PONV
Sponsor:
Ajou University School of Medicine
Organization:
Ajou University School of Medicine
Study Overview
Official Title:
The Effects of Anesthetic Techniques and Palonosetron Administration on the Incidence of Postoperative Nausea and Vomiting in the Women Patients Undergoing Thyroidectomy
Status:
COMPLETED
Status Verified Date:
2017-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The incidence of postoperative nausea and vomiting PONV after thyroidectomy have been shown to be relatively high compared other surgeries with a reported incidence 65-75 PONV may increase patient discomfort delay patient discharge and increase the cost of patient care the risk of postoperative bleeding which may potentially cause airway obstruction
It is reported that the maintenance of anesthesia with propofol-remifentanil or sevoflurane-propofol-remifentanil decreased the incidence of PONV compared sevoflurane alone but failed to demonstrate the decreased incidence of PONV in 6-24 hr postoperative period in patients undergoing thyroidectomy Administration of Palonosetron newly developed 5-HT3 antagonists with long half life 48 hrs may decrease the incidence of PONV particularly during this period
The purpose of this study was to evaluate and compare the incidence of PONV after thyroidectomy with three different anesthetic methods sevoflurane or sevoflurane-propofol-remifentanil or sevoflurane-propofol-remifentanil-palonosetron in woman patients
It is reported that the maintenance of anesthesia with propofol-remifentanil or sevoflurane-propofol-remifentanil decreased the incidence of PONV compared sevoflurane alone but failed to demonstrate the decreased incidence of PONV in 6-24 hr postoperative period in patients undergoing thyroidectomy Administration of Palonosetron newly developed 5-HT3 antagonists with long half life 48 hrs may decrease the incidence of PONV particularly during this period
The purpose of this study was to evaluate and compare the incidence of PONV after thyroidectomy with three different anesthetic methods sevoflurane or sevoflurane-propofol-remifentanil or sevoflurane-propofol-remifentanil-palonosetron in woman patients
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None