Ignite Creation Date:
2024-05-06 @ 8:41 AM
Last Modification Date:
2024-10-26 @ 12:03 PM
Study NCT ID:
NCT02792387
Status:
COMPLETED
Last Update Posted:
2017-10-11
First Post:
2016-05-16
Brief Title:
The Role of CVP and EF in Patients With Cardio-renal Syndromes
Sponsor:
Tbilisi State University
Organization:
Tbilisi State University
Study Overview
Official Title:
Some Characteristics of Interaction Between Heart and Kidneys in Cardio-Renal Syndrome Type 1 and Type 2
Status:
COMPLETED
Status Verified Date:
2017-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
RoCVPinCRSs
Brief Summary:
The aim of the study is to explore association between increased central venous pressure Ejection Fraction and renal dysfunction eGFR in patients with Cardio-Renal Syndromes type 1 and 2 The pilot study was set to provide the expected correlation coefficient for a sample size determination of the subsequent study
Detailed Description:
OBJECTIVES
The aim of the study is to explore association between increased central venous pressure CVP Ejection Fraction EF and renal dysfunction eGFR in patients with Cardio-Renal Syndromes type 1 and 2
BACKGROUND
The pathophysiology of impaired renal function in cardiovascular disease is multifactorial Recent investigations suggest that management of patients based on low-flow theory does not lead to improved outcomes Relative importance of right heart dysfunction manifested as increased CVP has not been evaluated Precise understanding of bidirectional pathways by which the heart and kidneys influence each other is necessary to define optimal treatment strategies specific to the subtypes as therapies directed towards one organ system may have beneficial or unfavorable effects on the other
METHODS
The study is of non-experimental observational type based on retrospective chart review The patients personal identifiers are concealed and an anonymized datasets used unique code given to each patient which is kept secure under the control of hospital staff
The aim of the study is to explore association between increased central venous pressure CVP Ejection Fraction EF and renal dysfunction eGFR in patients with Cardio-Renal Syndromes type 1 and 2
BACKGROUND
The pathophysiology of impaired renal function in cardiovascular disease is multifactorial Recent investigations suggest that management of patients based on low-flow theory does not lead to improved outcomes Relative importance of right heart dysfunction manifested as increased CVP has not been evaluated Precise understanding of bidirectional pathways by which the heart and kidneys influence each other is necessary to define optimal treatment strategies specific to the subtypes as therapies directed towards one organ system may have beneficial or unfavorable effects on the other
METHODS
The study is of non-experimental observational type based on retrospective chart review The patients personal identifiers are concealed and an anonymized datasets used unique code given to each patient which is kept secure under the control of hospital staff
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None