Ignite Creation Date:
2024-05-06 @ 8:38 AM
Last Modification Date:
2024-10-26 @ 12:03 PM
Study NCT ID:
NCT02785809
Status:
UNKNOWN
Last Update Posted:
2016-05-30
First Post:
2016-05-25
Brief Title:
Ovarian Function and Reserve Parameters After Discontinuation of Long-term Use of Oral Contraception
Sponsor:
Anders Nyboe Andersen
Organization:
Rigshospitalet Denmark
Study Overview
Official Title:
Recovery of Ovarian Function and Reserve Parameters After Discontinuation of Long-term Use of Oral Contraception Is the Recovery Period Related to AMH
Status:
UNKNOWN
Status Verified Date:
2016-05
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to investigate whether there is a correlation between anti-Müllerian hormone during long-term use of combined oral contraceptives and the recovery time before recovered menstrual cycle after discontinuation of oral contraceptives
Detailed Description:
Background
Hormonal contraception is widely used among women worldwide 50-89 of all women in the Western countries use oral contraception at some point in their lives Oral contraceptives OC suppress the hypothalamic-pituitary-ovarian axis through a negative feedback of ethinyl estradiol and progestins and thereby potentially influence the markers of ovarian reserve due to a suppressed release of gonadotropins which will impair the growth of antral follicles
Methods and Materials
Participants for this studies will be included through the Fertility Assessment and Counseling Clinic Rigshospitalet Herlev- and Hvidovre Hospital
Inclusion criteria Use of oral contraception for study 3 at least during the last three years
Exclusion criteria Known infertility known thyroid disease
Aims
Study 3 Investigate the ovarian reserve markers after discontinuation of OC over a period of three months in women with a history of long-term OC use The women will be followed with serial ultrasounds and blood samples and will complete a menstrual calendar
Hormonal contraception is widely used among women worldwide 50-89 of all women in the Western countries use oral contraception at some point in their lives Oral contraceptives OC suppress the hypothalamic-pituitary-ovarian axis through a negative feedback of ethinyl estradiol and progestins and thereby potentially influence the markers of ovarian reserve due to a suppressed release of gonadotropins which will impair the growth of antral follicles
Methods and Materials
Participants for this studies will be included through the Fertility Assessment and Counseling Clinic Rigshospitalet Herlev- and Hvidovre Hospital
Inclusion criteria Use of oral contraception for study 3 at least during the last three years
Exclusion criteria Known infertility known thyroid disease
Aims
Study 3 Investigate the ovarian reserve markers after discontinuation of OC over a period of three months in women with a history of long-term OC use The women will be followed with serial ultrasounds and blood samples and will complete a menstrual calendar
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None