Ignite Creation Date:
2024-05-06 @ 8:36 AM
Last Modification Date:
2024-10-26 @ 12:02 PM
Study NCT ID:
NCT02772900
Status:
COMPLETED
Last Update Posted:
2016-05-17
First Post:
2016-05-02
Brief Title:
Aging Nitrate Endothelial Function and Muscle Oxygenation
Sponsor:
Universidade Federal do Rio de Janeiro
Organization:
Universidade Federal do Rio de Janeiro
Study Overview
Official Title:
Effect of a Beetroot-based Nutritional Gel on Vascular Function and Forearm Muscle Oxygenation Responses in the Elderly at Cardiometabolic Risk
Status:
COMPLETED
Status Verified Date:
2016-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Aging has been associated with reduced bioavailability of nitric oxide NO and endothelial dysfunction Beetroot consumption a nitrate-rich food has been associated with increased NO bioconversion which may promote beneficial effects on vascular health The present study evaluated the effects of a beetroot-based nutritional gel BG on vascular function arterial stiffness and blood pressure in the elderly at cardiometabolic risk Twenty elderly individuals were submitted to BG and nitrate-depleted gel PLA interventions Brachial flow-mediated dilation FMD blood flow velocity BFV peak wave velocity PWVβ augmentation index AI stiffness parameter β pressure-strain elasticity modulus Ep arterial compliance AC muscle oxygenation and function were measured 90 min after interventions Urinary nitrate nitrite systolic blood pressure SBP diastolic blood pressure DBP and heart rate HR were measured at baseline 90 min and 150 min after interventions
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None