Ignite Creation Date:
2024-05-05 @ 12:03 PM
Last Modification Date:
2024-10-26 @ 9:19 AM
Study NCT ID:
NCT00227981
Status:
COMPLETED
Last Update Posted:
2013-06-25
First Post:
2005-09-26
Brief Title:
Maintenance Interpersonal Psychotherapy for Sustaining Remission of Depression
Sponsor:
University of Pittsburgh
Organization:
University of Pittsburgh
Study Overview
Official Title:
Maintenance Psychotherapies in Recurrent Depression Study II
Status:
COMPLETED
Status Verified Date:
2013-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will evaluate the effectiveness of maintenance interpersonal psychotherapy IPT in preventing relapse of depression in women who have required combined psychotherapy and pharmacotherapy treatment to obtain a remission of depression symptoms
Detailed Description:
Depression is a serious medical illness that can recur more than once in a persons lifetime Effective treatment methods are needed to maintain a state of remission in people who have had prior episodes of depression IPT is a brief and highly structured type of psychotherapy that addresses interpersonal issues associated with depression Previous studies have shown that it is an effective method for treating depression This study will evaluate the effectiveness of maintenance ITP in preventing relapse of depression in women who have required combined psychotherapy and pharmacotherapy treatment to obtain remission of depressive symptoms
Participants in this open label study will be recruited from a previous study Maintenance Psychotherapy in Recurrent Depression Study I In this study participants will initially receive weekly sessions of IPT as well as medication treatment with fluoxetine Any participants who do not reach remission of depressive symptoms after 6 weeks will be given other standard treatments for depression Once remission of depressive symptoms is reached participants will continue receiving weekly IPT and fluoxetine treatment for 20 weeks After 20 weeks fluoxetine treatment will be discontinued and all participants will receive IPT alone for 6 weeks before entering the maintenance phase of the study Upon entrance into this phase participants will be randomly assigned to receive IPT weekly biweekly or monthly for 18 months Functioning and depressive symptoms will be assessed at Month 24
Participants in this open label study will be recruited from a previous study Maintenance Psychotherapy in Recurrent Depression Study I In this study participants will initially receive weekly sessions of IPT as well as medication treatment with fluoxetine Any participants who do not reach remission of depressive symptoms after 6 weeks will be given other standard treatments for depression Once remission of depressive symptoms is reached participants will continue receiving weekly IPT and fluoxetine treatment for 20 weeks After 20 weeks fluoxetine treatment will be discontinued and all participants will receive IPT alone for 6 weeks before entering the maintenance phase of the study Upon entrance into this phase participants will be randomly assigned to receive IPT weekly biweekly or monthly for 18 months Functioning and depressive symptoms will be assessed at Month 24
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| DSIR 950309-9905 | None | None | None |