Ignite Creation Date:
2024-05-05 @ 12:02 PM
Last Modification Date:
2024-10-26 @ 9:19 AM
Study NCT ID:
NCT00220246
Status:
UNKNOWN
Last Update Posted:
2007-03-01
First Post:
2005-09-20
Brief Title:
Clinical and Molecular Characterization of Familial Microsatellite Stable Colorectal Cancer
Sponsor:
Radboud University Medical Center
Organization:
Radboud University Medical Center
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2007-02
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Two major genetic pathways leading to colorectal carcinoma can well be distinguished the suppressor pathway which is characterized by inactivation of tumor-suppressor genes and the mutator pathway which is characterized by microsatellite instability The purpose of this study is to explore a third putative pathway microsatellite and chromosome stable colorectal cancer where an alternative cancer-causative mechanism might play a role
Detailed Description:
Patients with familial colorectal cancer will be characterized with respect to family history medical history and demographic characteristics The histopathology of the tumors will be reviewed Tumor specimens will be analysed on molecular defects
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None