Ignite Creation Date:
2024-05-06 @ 8:27 AM
Last Modification Date:
2024-10-26 @ 12:01 PM
Study NCT ID:
NCT02748798
Status:
TERMINATED
Last Update Posted:
2023-04-25
First Post:
2016-04-19
Brief Title:
Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders
Sponsor:
Thunder Bay Regional Health Research Institute
Organization:
Thunder Bay Regional Health Research Institute
Study Overview
Official Title:
Developing Optimal Parameters for Hyperpolarized Noble Gas 3He and 129Xe and Inert Fluorinated Gas Magnetic Resonance Imaging of Lung Disorders
Status:
TERMINATED
Status Verified Date:
2024-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Funding is no longer available due to the failure to enroll the target number of participants within the required timeframe
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this research is to optimize the MRI system to obtain ideal lung images using Hyperpolarized HP Noble and Inert Fluorinated Gases as contrast agents Lung coils tuned to the frequencies of these gases will be used This study will take place at TBRHSC in the Cardiorespiratory Department and in the Research MRI facility
Detailed Description:
MR images of the lung obtained using HP 3He HP 129Xe and inert fluorinated gases essentially show the distribution of the inhaled gas inside the lungs Measurements can be performed on these images to provide additional information that can be related to pulmonary function
Participation will involve at least two study visits During the first visit participants will provide written informed consent and undergo eligibility screening Study drug administration use of the investigational devices and MR imaging for this study will be performed at the 3T Research MRI at the Thunder Bay Regional Health Sciences Centre TBRHSC Pulmonary Function Tests PFTs will be performed at TBRHSC by a Registered Respiratory Therapist RRT and an MR Tech will be present for the duration of participant scans
Participants will be placed in the MRI with the appropriate chest coil wrapped around them like a vest Several inhalation procedures will be carried out during scanning Participants safety will be closely monitored throughout the entire study
Participation will involve at least two study visits During the first visit participants will provide written informed consent and undergo eligibility screening Study drug administration use of the investigational devices and MR imaging for this study will be performed at the 3T Research MRI at the Thunder Bay Regional Health Sciences Centre TBRHSC Pulmonary Function Tests PFTs will be performed at TBRHSC by a Registered Respiratory Therapist RRT and an MR Tech will be present for the duration of participant scans
Participants will be placed in the MRI with the appropriate chest coil wrapped around them like a vest Several inhalation procedures will be carried out during scanning Participants safety will be closely monitored throughout the entire study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None