Ignite Creation Date:
2024-05-06 @ 8:24 AM
Last Modification Date:
2024-10-26 @ 11:59 AM
Study NCT ID:
NCT02730910
Status:
COMPLETED
Last Update Posted:
2018-04-02
First Post:
2016-01-21
Brief Title:
Anthocyanin Phenolic Acids Bioavailability Antioxidant Capacity After Consumption of Purple Wheat Products in Adults
Sponsor:
University of Guelph
Organization:
University of Guelph
Study Overview
Official Title:
Bioavailability of Anthocyanins and Phenolic Acids and Changes in Blood Antioxidant Capacity After Consumption of Purple Wheat Anthocyanin-enriched Crackers and Granola Bars by Healthy Adult Participants
Status:
COMPLETED
Status Verified Date:
2018-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This study will determine the bioavailability of anthocyanins and phenolic compounds from two purple wheat products ie bran-enriched wholegrain purple wheat crackers and bran-enriched wholegrain purple wheat granola bars Crackers are an example of a baked processed product The purple wheat granola bars are an example of a food product that requires much less intensive preparation and cooking compared to the crackers A comparison of bioavailability between these two products should provide insights about how different processes and food matrix influence anthocyanin bioavailability and metabolism
Detailed Description:
This study will determine the bioavailability of anthocyanins and phenolic compounds from two purple wheat products ie bran-enriched wholegrain purple wheat crackers and bran-enriched wholegrain purple wheat granola bars Crackers are an example of a baked processed product The purple wheat granola bars are an example of a food product that requires much less intensive preparation and cooking compared to the crackers A comparison of bioavailability between these two products should provide insights about how different processes and food matrix influence anthocyanin bioavailability and metabolism The study is a crossover investigation with 8 men and 8 women who will adhere to a low anthocyanin and low phenolic diet for the duration and complete 2 postprandial study visits where in random order they will consume either the crackers or granola bars Blood and urine will be collected at baseline and postprandially for the analysis of anthocyanins and their metabolites and phenolic acids and determination of antioxidant capacity
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None