Ignite Creation Date:
2024-05-06 @ 8:15 AM
Last Modification Date:
2024-10-26 @ 11:58 AM
Study NCT ID:
NCT02704468
Status:
COMPLETED
Last Update Posted:
2016-07-19
First Post:
2016-02-29
Brief Title:
FGF21 Can Help Predicting Arterial Stiffness Measured by Cardio-ankle Vascular Index in Renal Transplant Patients
Sponsor:
Bangkok Metropolitan Administration Medical College and Vajira Hospital
Organization:
Bangkok Metropolitan Administration Medical College and Vajira Hospital
Study Overview
Official Title:
FGF21 Can Help Predicting Arterial Stiffness Measured by Cardio-ankle Vascular Index in Renal Transplant Patients
Status:
COMPLETED
Status Verified Date:
2016-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CAVIFGF21
Brief Summary:
Chronic kidney diseaseCKD patients have high incidence of coronary artery problems event after renal transplantation And remain a major cause of mortality The major risk marker is arterial stiffness The cardio-ankle vascular index CAVI is a new index of overall stiffness and can estimated the risk of atherosclerosis
Fibroblast growth factor 21 FGF-21 is a metabolic regulator that plays important role in cardiac remodeling elevated FGF-21 have been reported in coronary heart disease or carotid artery plaque and could be biomarkers for atherosclerosis disease Investigators aimed to study the association between CAVI and FGF-21 and their relations to various parameters that can contribute to cardiovascular disease eg homocysteine Echocardiogram findings and other traditional basic factors
Fibroblast growth factor 21 FGF-21 is a metabolic regulator that plays important role in cardiac remodeling elevated FGF-21 have been reported in coronary heart disease or carotid artery plaque and could be biomarkers for atherosclerosis disease Investigators aimed to study the association between CAVI and FGF-21 and their relations to various parameters that can contribute to cardiovascular disease eg homocysteine Echocardiogram findings and other traditional basic factors
Detailed Description:
A total of 90 participants who underwent renal transplant were included in the study The following measures were done and laboratory data were collected CAVI Ecchocariogram Homocysteine Hs-CRP Carotid IMT FGF-21 Medication after renal transplantation incidence of cardiovascular disease correlation between categorical data was done by using Pearsons correlation test and multiple regression analysis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None