Ignite Creation Date:
2024-05-06 @ 8:15 AM
Last Modification Date:
2024-10-26 @ 11:57 AM
Study NCT ID:
NCT02693899
Status:
COMPLETED
Last Update Posted:
2019-02-19
First Post:
2016-02-17
Brief Title:
Prospective Study on the Feasibility of Plasma FLT3-Ligand Assay to Achieve a First Estimate of Its Prognostic Value on the Outcome of Patients Treated Intensively for Acute Leukemia
Sponsor:
Nantes University Hospital
Organization:
Nantes University Hospital
Study Overview
Official Title:
Monocentric Biological Uncontrolled Prospective Study on the Feasibility of Plasma FLT3 Ligand Assay to Achieve a First Estimate of Its Prognostic Value on the Outcome of Patients Treated With Intensively for Acute Leukemia
Status:
COMPLETED
Status Verified Date:
2019-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
FLAMFLAL
Brief Summary:
Despite advances in their classification and treatment acute leukemia remain incurable disease for the majority of patients It is necessary to identify new prognostic markers of survival and new therapeutic targets to improve prognosis Some studies have shown that Fms-like tyrosine kinase 3-ligand FLT3-L could be interesting from this A more recent study from our group testing a novel therapy in acute lymphoblastic leukemia showed an increase of this marker in the blood of patients responding to treatment The aim of our prospective non-interventional study is to measure the plasma levels of FLT3-L at different times of the management of patients with acute lymphoblastic leukemia but also myeloid For this analyzes of the samples collected in the usual care will be conducted to study the relationship between the plasma concentration of FLT3-L and outcomes If there is any link the FLT3-L could serve as a predictor of treatment response
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None