Ignite Creation Date:
2024-05-06 @ 8:09 AM
Last Modification Date:
2024-10-26 @ 11:56 AM
Study NCT ID:
NCT02675543
Status:
COMPLETED
Last Update Posted:
2017-06-02
First Post:
2016-01-25
Brief Title:
Vitreous Inflammation in Standard and Heavy Silicone Oil
Sponsor:
Università degli Studi di Brescia
Organization:
Università degli Studi di Brescia
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2017-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The inflammatory response after prolonged retinal detachment and after vitreoretinal surgery has its apex in the development of PVR that occurs when retinal cells are exposed to the inflammatory milieu in the humor vitreous
This situation is common in complicated retinal detachment but is amplified after invasive surgery and by the use of intraocular tamponades that float over a subtle film of liquid where the inflammatory cytokines and growth factors reach the critical concentration over the inferior retina
Many authors have noted that the heavy tamponade are more prone to cause intraocular inflammation compared to standard silicone oil especially if they remain for several months in the eye
The purpose of this study is to measure the vitreous concentration of some of the most important cytokines involved in the inflammatory vitreal response
This situation is common in complicated retinal detachment but is amplified after invasive surgery and by the use of intraocular tamponades that float over a subtle film of liquid where the inflammatory cytokines and growth factors reach the critical concentration over the inferior retina
Many authors have noted that the heavy tamponade are more prone to cause intraocular inflammation compared to standard silicone oil especially if they remain for several months in the eye
The purpose of this study is to measure the vitreous concentration of some of the most important cytokines involved in the inflammatory vitreal response
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None