Ignite Creation Date:
2024-05-06 @ 8:07 AM
Last Modification Date:
2024-10-26 @ 11:56 AM
Study NCT ID:
NCT02676843
Status:
COMPLETED
Last Update Posted:
2019-12-06
First Post:
2016-01-15
Brief Title:
Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations
Sponsor:
Columbia University
Organization:
Columbia University
Study Overview
Official Title:
Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations
Status:
COMPLETED
Status Verified Date:
2019-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The study will investigate the ability of a new PET tracer 18F-AV-1451 to detect depositions of a protein called tau in the brains of people with a mutation in the tau gene that causes deposition of the protein and in people without the mutation Up to three 18F-AV-1451 scans will be performed one per year on control subjects without MAPT mutations presymptomatic mutation carriers and symptomatic mutation carriers
Detailed Description:
Approximately 40 of cases of Frontotemporal lobar Degeneration FTLD are also associated with abnormal deposition of tau protein The purpose of this study is to image MAPT mutation carriers and their non-carrier relatives in order to study the use of this tracer as a biomarker in Frontotemporal Lobar Degeneration with tau deposition FTLD-tau
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01NS076837 | NIH | None | httpsreporternihgovquickSearchR01NS076837 |