Ignite Creation Date:
2024-05-06 @ 8:07 AM
Last Modification Date:
2024-10-26 @ 11:56 AM
Study NCT ID:
NCT02671344
Status:
TERMINATED
Last Update Posted:
2020-02-12
First Post:
2016-01-25
Brief Title:
Determining the Genetic Profile in Semen Donors With Pregnancy Donor Versus no Pregnancy Obtained in TRA
Sponsor:
IVI Bilbao
Organization:
IVI Bilbao
Study Overview
Official Title:
Determination of Gene Profiling in Semen Donors With Pregnancy Versus no Donor Gestation Obtained in Assisted Reproduction Treatments
Status:
TERMINATED
Status Verified Date:
2020-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
could not be obtained enough sperm RNA is highly fragmented and very difficult to purify
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Microarray experiments to assess the expression of thousands of genes providing vast amount of information
Because the molecular requirements in the different processes related to playbackon the hypothesis that there may be more apt semen samples for technical or other assuming molecular differences in RNA content messengers or gene expression profile between the They getting semen samples in gestation versus those who do not
In an attempt to give a functional data obtained view it is to find out how many of these genes in donors who have obtained gestation they are differentially expressed in playback related processes against those donors who did not get pregnant
Because the molecular requirements in the different processes related to playbackon the hypothesis that there may be more apt semen samples for technical or other assuming molecular differences in RNA content messengers or gene expression profile between the They getting semen samples in gestation versus those who do not
In an attempt to give a functional data obtained view it is to find out how many of these genes in donors who have obtained gestation they are differentially expressed in playback related processes against those donors who did not get pregnant
Detailed Description:
MRNA assembly is characterized by using microarrays on semen samples from donors included in the donation program of the clinic
This process is performed in donors who have generated at least 3 pregnancies compared those samples however were not a function of gestation assisted reproduction technique used
Consequently differential expression of genes are identified in assisted reproduction treatment cycles from IAD IVF or ICSI
This process is performed in donors who have generated at least 3 pregnancies compared those samples however were not a function of gestation assisted reproduction technique used
Consequently differential expression of genes are identified in assisted reproduction treatment cycles from IAD IVF or ICSI
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None