Ignite Creation Date:
2024-05-06 @ 8:02 AM
Last Modification Date:
2024-10-26 @ 11:55 AM
Study NCT ID:
NCT02655718
Status:
UNKNOWN
Last Update Posted:
2016-01-14
First Post:
2015-12-29
Brief Title:
Short and Long Term Outcomes of Acute Coronary Syndrome in Patients With Non Obstructive Coronary Atherosclerosis
Sponsor:
Russian Academy of Medical Sciences
Organization:
Russian Academy of Medical Sciences
Study Overview
Official Title:
Short and Long Term Outcomes of Acute Coronary Syndrome in Patients With Non Obstructive Coronary Atherosclerosis
Status:
UNKNOWN
Status Verified Date:
2016-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NOCA
Brief Summary:
The purpose of the study is to assess short and long term outcomes of acute coronary syndrome in patients with non obstructive coronary atherosclerosis to optimize the algorithm for diagnosis and to evaluate its effectiveness
Detailed Description:
The study non randomized opened controlled Cardiovascular Magnetic - resonance imaging reveals both ischemic and non-ischemic causes of acute coronary syndrome Currently it is the best method for Imaging and damage assessment of myocardial viability in coronary atherosclerosis and noncoronary injuries VYuUsov 2012
Taking into account the results of previous D Kawecki B Morawiec P Monney 2015 research it can be concluded that the introduction of cardiovascular magnetic resonance imaging into routine practice will change the structure of morbidity among patients with acute coronary syndrome and non obstructive coronary atherosclerosis The research was conducted on small groups of patients and therefore further data acquisition is required
It is planned to study 200 patients with acute coronary syndrome On admission they will receive the standard treatment of ACS with and without ST elevation Within 72 hours they will performed diagnostic coronary angiography If in case of non stenotic atherosclerosis of coronary artery normal stenosis 50 patients are planned for cardiac contrast MRI which will identify both ischemic and non-ischemic causes of acute coronary syndrome At 30 days 6 months 12 months the researchers will assess the clinical condition of the patients perform cardiac ultrasound for the evaluation of myocardial contractile function evaluate the incidence rate of secondary endpoints
Taking into account the results of previous D Kawecki B Morawiec P Monney 2015 research it can be concluded that the introduction of cardiovascular magnetic resonance imaging into routine practice will change the structure of morbidity among patients with acute coronary syndrome and non obstructive coronary atherosclerosis The research was conducted on small groups of patients and therefore further data acquisition is required
It is planned to study 200 patients with acute coronary syndrome On admission they will receive the standard treatment of ACS with and without ST elevation Within 72 hours they will performed diagnostic coronary angiography If in case of non stenotic atherosclerosis of coronary artery normal stenosis 50 patients are planned for cardiac contrast MRI which will identify both ischemic and non-ischemic causes of acute coronary syndrome At 30 days 6 months 12 months the researchers will assess the clinical condition of the patients perform cardiac ultrasound for the evaluation of myocardial contractile function evaluate the incidence rate of secondary endpoints
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None