Ignite Creation Date:
2024-05-05 @ 10:23 AM
Last Modification Date:
2024-10-26 @ 9:04 AM
Study NCT ID:
NCT00005141
Status:
COMPLETED
Last Update Posted:
2016-05-13
First Post:
2000-05-25
Brief Title:
Minneapolis Childrens Blood Pressure Study
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2000-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To examine environmental and familial correlates of childhood blood pressure in order to predict elevated blood pressure in young adulthood Also to investigate the phenomena of tracking of blood pressure and obesity from childhood to young adulthood
Detailed Description:
BACKGROUND
Hypertension has been clearly identified as a major risk factor for coronary heart disease and stroke Hypertension screening and intervention programs for children are based on the concept that high normal blood pressure may be the childhood antecedent of adult hypertension or that blood pressure tracks through childhood adolescence and adulthood Blood pressure tracking has been well established for adults and young adults but results from various studies in children are controversial At a Symposium on High Blood Pressure in the Young in 1979 it was concluded that there was insufficient information to recommend specific interventions for prepubertal children with blood pressure levels in the upper percentiles of the blood pressure distribution Studies of longer duration with large population sizes and repeated blood pressure measurements over time were required to determine if blood pressure levels at these young ages were predictive of adult hypertension
DESIGN NARRATIVE
In the Spring of 1978 a total of 10423 children ages 6-8 were screened A subsample was invited to join the study of blood pressure measurement The sample was selected as follows all children in the top five percent of the initial systolic blood pressure distribution all children in the bottom five percent of the initial systolic blood pressure distribution a random sample of one in two of the remaining Black children a random sample of one in nine of the remaining white children and all the remaining children of other races Included were families of about 200 Native American children Of 2641 selected children 878 refused leaving a sample of 1753 Baseline data on age race sex triceps skinfold thickness dietary history urinary sodium and potassium excretion physiological measures life event changes medical history demographic data and body size measurements of children and their parents were collected at the first home interview conducted between 1978 and 1979 The children were followed twice per year in 1978 to 1980 and 1982 to 1985 for blood pressure and body size Annual measurements were made of blood pressure height weight skinfold thickness and body girths Screenings continued through early 1991 when the cohort was 19-21 years of age
Several substudies were conducted including the relationship of red blood cell cation transport to essential hypertension Type A behavior assessments and familial aggregation of coronary-prone behavior
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Hypertension has been clearly identified as a major risk factor for coronary heart disease and stroke Hypertension screening and intervention programs for children are based on the concept that high normal blood pressure may be the childhood antecedent of adult hypertension or that blood pressure tracks through childhood adolescence and adulthood Blood pressure tracking has been well established for adults and young adults but results from various studies in children are controversial At a Symposium on High Blood Pressure in the Young in 1979 it was concluded that there was insufficient information to recommend specific interventions for prepubertal children with blood pressure levels in the upper percentiles of the blood pressure distribution Studies of longer duration with large population sizes and repeated blood pressure measurements over time were required to determine if blood pressure levels at these young ages were predictive of adult hypertension
DESIGN NARRATIVE
In the Spring of 1978 a total of 10423 children ages 6-8 were screened A subsample was invited to join the study of blood pressure measurement The sample was selected as follows all children in the top five percent of the initial systolic blood pressure distribution all children in the bottom five percent of the initial systolic blood pressure distribution a random sample of one in two of the remaining Black children a random sample of one in nine of the remaining white children and all the remaining children of other races Included were families of about 200 Native American children Of 2641 selected children 878 refused leaving a sample of 1753 Baseline data on age race sex triceps skinfold thickness dietary history urinary sodium and potassium excretion physiological measures life event changes medical history demographic data and body size measurements of children and their parents were collected at the first home interview conducted between 1978 and 1979 The children were followed twice per year in 1978 to 1980 and 1982 to 1985 for blood pressure and body size Annual measurements were made of blood pressure height weight skinfold thickness and body girths Screenings continued through early 1991 when the cohort was 19-21 years of age
Several substudies were conducted including the relationship of red blood cell cation transport to essential hypertension Type A behavior assessments and familial aggregation of coronary-prone behavior
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL019877 | NIH | None | httpsreporternihgovquickSearchR01HL019877 |