Ignite Creation Date:
2024-05-06 @ 7:58 AM
Last Modification Date:
2024-10-26 @ 11:55 AM
Study NCT ID:
NCT02648789
Status:
COMPLETED
Last Update Posted:
2018-08-09
First Post:
2015-11-19
Brief Title:
Validation of DNA Methylation Biomarkers for Oral Cancer Detection
Sponsor:
Taipei Veterans General Hospital Taiwan
Organization:
Taipei Veterans General Hospital Taiwan
Study Overview
Official Title:
Validation of DNA Methylation Biomarkers for Oral Cancer Detection
Status:
COMPLETED
Status Verified Date:
2017-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to investigate the correlation between DNA methylation and the treatment and recurrence of oral cancer
Detailed Description:
In this study investigators plan to recruit 4050 patients who had or currently has oral cancer The study procedures are as below
After the Informed Consent Form is signed swab from the lesion site and normal site to obtain oral epithelial cells
Collect tissue from the tumor site and the non-cancerous matched site from the surgery or the tissue bank
Collect oral swab from the lesion site and the normal site when patients return to the clinic for a regular follow-up
Specimens will be collected for DNA methylation testing and the results will be compared with patients clinical diagnosis It is expected that the relationship between DNA methylation oral cancer and the recurrence of oral cancer will be found
After the Informed Consent Form is signed swab from the lesion site and normal site to obtain oral epithelial cells
Collect tissue from the tumor site and the non-cancerous matched site from the surgery or the tissue bank
Collect oral swab from the lesion site and the normal site when patients return to the clinic for a regular follow-up
Specimens will be collected for DNA methylation testing and the results will be compared with patients clinical diagnosis It is expected that the relationship between DNA methylation oral cancer and the recurrence of oral cancer will be found
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None