Ignite Creation Date:
2024-05-05 @ 12:01 PM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00211653
Status:
COMPLETED
Last Update Posted:
2007-09-19
First Post:
2005-09-13
Brief Title:
Acetylcysteine in the Prevention of Renal Failure After Bypass Surgery
Sponsor:
Minneapolis Veterans Affairs Medical Center
Organization:
Minneapolis Veterans Affairs Medical Center
Study Overview
Official Title:
Single Center Randomized Clinical Trial of the Effects of Acetylcysteine in the Prevention of Postoperative Renal Failure
Status:
COMPLETED
Status Verified Date:
2007-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine if Acetylcysteine is effective in preventing renal failure associated with cardiac surgery
Detailed Description:
Postoperative renal dysfunction is a predictor of significant morbidity and mortality among patients undergoing cardiac surgery The mortality associated with coronary artery by-pass surgery increases from 2 to almost 19 in patients with renal failure and approaches 60 in patients who require hemodialysis Patients with preoperative renal dysfunction referred for coronary artery by pass surgery have an extraordinarily high risk of requiring postoperative dialysis For example among those patients with preoperative creatinine 25 mgdL almost 50 require hemodialysis
Comparison N-Acetylcysteine is superior to placebo in preventing renal failure after cardiac surgery
Comparison N-Acetylcysteine is superior to placebo in preventing renal failure after cardiac surgery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None