Viewing Study NCT00213551



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Study NCT ID: NCT00213551
Status: COMPLETED
Last Update Posted: 2013-06-18
First Post: 2005-09-13

Brief Title: Glutamine and Intestinal Protein Metabolism
Sponsor: University Hospital Rouen
Organization: University Hospital Rouen

Study Overview

Official Title: Comparative Effects of Glutamine and Glucose on Intestinal Protein Metabolism in Healthy Humans
Status: COMPLETED
Status Verified Date: 2013-06
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: Gut barrier plays a major role in defence of the organism During catabolic states like major surgery or inflammation gut barrier could be altered It has been reported that preoperative nutritional support may have beneficial effects on clinical outcome in patients with surgery on gastrointestinal tract Glutamine which is a conditionally essential amino have been reported to modulate inflammatory antioxidant responses and protein metabolism in intestine In addition glutamine supply improves clinical outcome in critically ill patients Antioxidant micronutrients may also have some beneficial effects in intestine by improving antioxidant response and might also regulate protein expression Nevertheless effects of glutamine combined to antioxidant micronutrients have not been evaluated

Thus the aim of this study will be to assess the influence of glutamine and glutamine-antioxidant micronutrients-containing solutions on intestinal response in humans
Detailed Description: None

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None