Ignite Creation Date:
2024-05-06 @ 7:55 AM
Last Modification Date:
2024-10-26 @ 11:53 AM
Study NCT ID:
NCT02627183
Status:
RECRUITING
Last Update Posted:
2023-02-28
First Post:
2015-12-08
Brief Title:
Circulating BDNF in Patients With Atrial Fibrillation Undergoing Catheter Ablation or Exercise Training
Sponsor:
Ottawa Heart Institute Research Corporation
Organization:
Ottawa Heart Institute Research Corporation
Study Overview
Official Title:
Circulating Brain-derived Neurotrophic Factor BDNF in Patients With Atrial Fibrillation Undergoing Catheter Ablation or Exercise Training A Pilot Study NEURO-AF
Status:
RECRUITING
Status Verified Date:
2023-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NEURO-AF
Brief Summary:
The main purpose of this project is to determine the impact of atrial fibrillation interventions catheter ablation and exercise training on circulating BDNF concentrations in patients with atrial fibrillation It also seeks to determine if there is a relation between circulating BDNF concentrations and mental health depression severity quality of life and symptoms among those undergoing interventions for atrial fibrillation catheter ablation or exercise training
Detailed Description:
The main purpose of this project is to determine the impact of atrial fibrillation interventions catheter ablation and exercise training on circulating BDNF concentrations in patients with atrial fibrillation It also seeks to determine if there is a relation between circulating BDNF concentrations and mental health depression severity quality of life and symptoms among those undergoing interventions for atrial fibrillation catheter ablation or exercise training Using a pre-post study design the investigators will explore interventions in two subsets of patients at the opposite end of the atrial fibrillation clinical spectrum Arm 1 patients with paroxysmal atrial fibrillation will undergo catheter ablation n100 Arm 2 patients with permanent or persistent atrial fibrillation will perform exercise training 2 times weekly for 12 weeks n100 Total sample size will be 200 participants All measurements will be performed at baseline and follow-up
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None