Ignite Creation Date:
2024-05-06 @ 7:53 AM
Last Modification Date:
2024-10-26 @ 11:53 AM
Study NCT ID:
NCT02621736
Status:
COMPLETED
Last Update Posted:
2021-12-13
First Post:
2015-11-25
Brief Title:
Copeptin for Prediction of Treatment Response in Children With Monosymptomatic Nocturnal Enuresis MEN
Sponsor:
University Hospital Basel Switzerland
Organization:
University Hospital Basel Switzerland
Study Overview
Official Title:
Copeptin for Prediction of Treatment Response in Children With Monosymptomatic Nocturnal Enuresis MEN
Status:
COMPLETED
Status Verified Date:
2021-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
COMEN
Brief Summary:
Monosymptomatic nocturnal enuresis MEN is a common problem in children affecting 7-10 of all 7 year olds MEN is often leading to psychosocial problems because of its burden and stigmatism
The only available medical treatment option is the vasopressin analogum Desmopressin However according to the literature only one third of patients shows a good treatment response defined as more than 90 of reduced bed wetting Furthermore treatment with Desmopressin may lead to psychosocial problems high costs and potentially dangerous side effects like water intoxication and hypertension
Copeptin mirroring arginine vasopressin AVP has been shown to be significantly lower in patients with MEN compared to controls and lower in patients with severe bed wetting compared to patients with only slight bed wetting
The only available medical treatment option is the vasopressin analogum Desmopressin However according to the literature only one third of patients shows a good treatment response defined as more than 90 of reduced bed wetting Furthermore treatment with Desmopressin may lead to psychosocial problems high costs and potentially dangerous side effects like water intoxication and hypertension
Copeptin mirroring arginine vasopressin AVP has been shown to be significantly lower in patients with MEN compared to controls and lower in patients with severe bed wetting compared to patients with only slight bed wetting
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None