Ignite Creation Date:
2024-05-06 @ 7:51 AM
Last Modification Date:
2024-10-26 @ 11:53 AM
Study NCT ID:
NCT02613247
Status:
UNKNOWN
Last Update Posted:
2016-11-08
First Post:
2015-11-20
Brief Title:
Intra-articular Hyaluronic Acid Injection for Therapy-resistant Patellofemoral Pain Syndrome
Sponsor:
University of Calgary
Organization:
University of Calgary
Study Overview
Official Title:
Intra-articular Hyaluronic Acid Injection for Therapy-resistant Patellofemoral Pain Syndrome an Open-label Randomized Delayed-start Clinical Trial
Status:
UNKNOWN
Status Verified Date:
2016-11
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Patellofemoral pain syndrome PFPS is the most common overuse injury seen in the athletic population particularly amongst runners The standard of care treatment for PFPS is a comprehensive active rehabilitation program Eighty percent of patients with PFPS report improvement in their symptoms with such a program Unfortunately the remaining twenty percent fail to achieve adequate symptom relief with rehabilitation alone Considering the enormous number of individuals running for fitness PFPS represents a significant challenge to public health as the investigators strive to encourage active living in our society
A relationship between PFPS and the development of patellofemoral osteoarthritis PFOA has been suggested in scientific literature Given that intra-articular viscosupplementation hyaluronic acid injections have shown clinically significant symptom improvement in knee osteoarthritis and PFPS is likely on the same spectrum the investigators propose a trial for therapy-resistant PFPS
Hyaluronic acid is a naturally occurring molecule found in the synovial fluid of freely movable joints such as the knee It is believed to contribute to lubrication and cushioning in these joints The composition of synovial fluid within arthritic joints is altered resulting in reduced fluid viscosity and elasticity One modern formulation of hyaluronic acid is Hylan G-F 20 Synvisc-One Sanofi Canada This treatment is offered as a single injection and will be utilized in this clinical trial
A relationship between PFPS and the development of patellofemoral osteoarthritis PFOA has been suggested in scientific literature Given that intra-articular viscosupplementation hyaluronic acid injections have shown clinically significant symptom improvement in knee osteoarthritis and PFPS is likely on the same spectrum the investigators propose a trial for therapy-resistant PFPS
Hyaluronic acid is a naturally occurring molecule found in the synovial fluid of freely movable joints such as the knee It is believed to contribute to lubrication and cushioning in these joints The composition of synovial fluid within arthritic joints is altered resulting in reduced fluid viscosity and elasticity One modern formulation of hyaluronic acid is Hylan G-F 20 Synvisc-One Sanofi Canada This treatment is offered as a single injection and will be utilized in this clinical trial
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None