Ignite Creation Date:
2024-05-06 @ 7:47 AM
Last Modification Date:
2024-10-26 @ 11:52 AM
Study NCT ID:
NCT02604628
Status:
COMPLETED
Last Update Posted:
2019-02-22
First Post:
2015-11-10
Brief Title:
Increasing Community-acquired Pneumonia Protocol Adherence by Antibiotic Stewardship
Sponsor:
UMC Utrecht
Organization:
UMC Utrecht
Study Overview
Official Title:
Community-acquired Pneumonia Increasing Protocol Adherence by Antibiotic Stewardship in a Stepped Wedge Cluster- Randomized Trial
Status:
COMPLETED
Status Verified Date:
2019-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CAP-PACT
Brief Summary:
The purpose of this study is to determine the effect of a multifaceted antibiotic stewardship intervention on protocol adherence of moderate-severe community-acquired pneumonia
Detailed Description:
The purpose of the study is to show a decrease in broad-spectrum antibiotics with a non-inferiority in 90-day mortality Hospitals with a pre-intervention protocol adherence of 70 are excluded from the primary analysis Primary analysis will be done with a mixed effects model with a random effects for clusters and time Crude outcomes and outcomes adjusted for potential confounders will be reported Primary analysis will be tested one-sided for a decrease in mortality Secondary analysis to test two-sided for mortality will be performed
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None