Ignite Creation Date:
2024-05-05 @ 12:00 PM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00207428
Status:
COMPLETED
Last Update Posted:
2006-05-16
First Post:
2005-09-13
Brief Title:
Antiepileptic Drug Carbamazepine in Treatment of Bronchial Asthma
Sponsor:
Centre of Chinese Medicine Georgia
Organization:
Centre of Chinese Medicine Georgia
Study Overview
Official Title:
Randomized Placebo Controlled Double Blind Study of Carbamazepine in Treatment of Bronchial Asthma
Status:
COMPLETED
Status Verified Date:
1999-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study was evaluation the efficacy of antiepileptic drug carbamazepine in the treatment of mild-to-severe bronchial asthma
Detailed Description:
Effective therapy of asthma still remains quite serious problem According current opinion of leading specialists asthma is an inflammatory disorder But asthma also is a paroxysmal disorder many specialists underline paroxysmal clinical picture of asthma According to some authors neurogenic inflammation may play important role in asthma mechanism But migraine and trigeminal neuralgia are also neurogenic inflammatory paroxysmal diseases and some antiepileptic drugs like carbamazepine and valproates are very effective in therapy of these diseases - more than in 80 of cases If bronchial asthma also is paroxysmal inflammatory disease we can suppose a possibility that some antiepileptic drugs also may show high efficacy in asthma therapy Taken in consideration this hypothesis we performed a double-blind placebo-controlled 3-month trial for evaluation of carbamazepine efficacy in treatment of patients with mild-to-severe bronchial asthma
Comparison Patients received investigational drug in addition to their usual routine antiasthmatic treatment compared to patients received placebo in addition to their usual routine antiasthmatic treatment
Comparison Patients received investigational drug in addition to their usual routine antiasthmatic treatment compared to patients received placebo in addition to their usual routine antiasthmatic treatment
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None