Ignite Creation Date:
2024-05-06 @ 7:38 AM
Last Modification Date:
2024-10-26 @ 11:50 AM
Study NCT ID:
NCT02573792
Status:
COMPLETED
Last Update Posted:
2021-06-22
First Post:
2015-10-09
Brief Title:
Optical Coherence Tomography and Optic Neuritis OCTON
Sponsor:
Fondation Ophtalmologique Adolphe de Rothschild
Organization:
Fondation Ophtalmologique Adolphe de Rothschild
Study Overview
Official Title:
Optical Coherence Tomography for the Etiological Diagnosis of Inflammatory Optic Neuritis
Status:
COMPLETED
Status Verified Date:
2021-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
OCTON
Brief Summary:
Optic neuritis ON can remain isolated or reveal a widespread and chronic disease of the central nervous system CNS a multiple sclerosis MS or more rarely a Devics neuromyelitis optica NMO or a systemic disease
The optical coherence tomography OCT is a retinal imaging technique to measure the thickness of the retina and its different layers with an accuracy of 4-6 µM
Costello et al have shown that approximately 75 of 54 MS patients have developed within 3 to 6 months after a ON a loss of 10 to 40 µM in the thickness of the peripapillary retinal nerve fiber layer RNFL
The etiologic diagnosis of ON has been transformed in recent years MS can now be diagnosed by McDonalds MRI criteria and NMO by the AQP4 antibodies anti-aquaporin- 4 antibodies and the anti-MOG myelin-oligodendrocyte glycoprotein antibodies
The diagnosis and prognosis value of the OCT in patients with ON is not well known
The optical coherence tomography OCT is a retinal imaging technique to measure the thickness of the retina and its different layers with an accuracy of 4-6 µM
Costello et al have shown that approximately 75 of 54 MS patients have developed within 3 to 6 months after a ON a loss of 10 to 40 µM in the thickness of the peripapillary retinal nerve fiber layer RNFL
The etiologic diagnosis of ON has been transformed in recent years MS can now be diagnosed by McDonalds MRI criteria and NMO by the AQP4 antibodies anti-aquaporin- 4 antibodies and the anti-MOG myelin-oligodendrocyte glycoprotein antibodies
The diagnosis and prognosis value of the OCT in patients with ON is not well known
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None