Ignite Creation Date:
2024-05-06 @ 7:35 AM
Last Modification Date:
2024-10-26 @ 11:50 AM
Study NCT ID:
NCT02562690
Status:
UNKNOWN
Last Update Posted:
2016-05-11
First Post:
2015-09-27
Brief Title:
Assessment of Thrombotic Status in Patients With Acute Coronary Syndrome
Sponsor:
University of Hertfordshire
Organization:
University of Hertfordshire
Study Overview
Official Title:
Assessment of Thrombotic Status in Patients With Acute Coronary Syndrome
Status:
UNKNOWN
Status Verified Date:
2016-05
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Impaired thrombotic status is associated with adverse cardiovascular events Patients with acute coronary syndrome ACS are at increased cardiovascular risk The aim of the study is to determine the usefulness of thrombotic status assessment in a large cohort of ACS patients managed with contemporary treatments to identify patients at risk of thrombosis and those at risk of bleeding complications
Detailed Description:
Patients presenting with acute coronary syndrome ACS are at increased risk of future cardiovascular events despite optimal medical treatment and coronary intervention Such events are usually caused by increased stickiness of the blood causing a blood clot thrombus to block arterial blood vessels in the heart Much of the medication to prevent recurrent thrombotic events increases the risk of bleeding complications Identification of patients at recurrent thrombotic risk could allow targeted treatment with potent antithrombotic medications with less potent agents in others to reduce bleeding The investigators will assess the stickiness of the blood ie thrombotic status in patients who are admitted to hospital with ACS at baseline at discharge from hospital and at 30 days post hospitalisation Blood stickiness will be tested using a number of tests of thrombotic status including thrombin generation assays Thromboelastography TEG and the near-patient point-of-care Global Thrombosis Test GTT The results will be evaluated to assess the effect of disease process and clinical state on blood stickiness to gain further understanding of the condition and form the basis for future studies aimed at identifying patients who are at high risk of future cardiovascular events
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None