Ignite Creation Date:
2024-05-06 @ 7:34 AM
Last Modification Date:
2024-10-26 @ 11:49 AM
Study NCT ID:
NCT02552537
Status:
COMPLETED
Last Update Posted:
2017-05-11
First Post:
2015-09-14
Brief Title:
iFAAM The Impact of Proton-pump Inhibitors Antacids on Threshold Dose Distributions
Sponsor:
University of Zurich
Organization:
University of Zurich
Study Overview
Official Title:
Integrated Approaches to Food Allergen and Allergy Risk Management iFAAM The Impact of Proton-pump Inhibitors Antacids on Threshold Dose Distributions
Status:
COMPLETED
Status Verified Date:
2017-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
iFAAM-PPI
Brief Summary:
In patients with a walnut allergy double blind placebo controlled food challenge with walnut will be combined with the intake of proton pump inhibitor PPI or with placebo to assess the impact of PPI on threshold level and on clinical manifestation
Detailed Description:
1 detailed case history blood sampling and prick testing with different foods will performed
2 double blind food provocation with with three meals containing either placebo or walnut in walnut allergic patients will be performed
3 the provocation will be combined with the intake of drug omeprazole or placebo mannitol blinded in capsules
2 double blind food provocation with with three meals containing either placebo or walnut in walnut allergic patients will be performed
3 the provocation will be combined with the intake of drug omeprazole or placebo mannitol blinded in capsules
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None