Ignite Creation Date:
2024-05-06 @ 7:29 AM
Last Modification Date:
2024-10-26 @ 11:49 AM
Study NCT ID:
NCT02548026
Status:
COMPLETED
Last Update Posted:
2015-09-14
First Post:
2015-09-08
Brief Title:
Meals and Grazing Study
Sponsor:
Fred Hutchinson Cancer Center
Organization:
Fred Hutchinson Cancer Center
Study Overview
Official Title:
Meals and Grazing Study
Status:
COMPLETED
Status Verified Date:
2015-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MAGS
Brief Summary:
The purpose of this study was to determine the effects of low vs high eating frequency EF on biomarkers of health and subjective appetite
Detailed Description:
Observational studies have demonstrated an inverse relationship between eating frequency EF obesity and other markers for disease risk It has been suggested that consumption of several small frequent meals may influence physiological mechanisms reducing the risk for disease and lowering appetite Participants in this randomized crossover study completed two intervention phases lasting three weeks each one of low eating frequency low-EF 3 eating occasionsday and one of high eating frequency high-EF 8 eating occasionsday Fasting C-reactive protein insulin-like growth factor and leptin were measured at baseline and endpoint of each phase and an optional subjective appetite testing session lasting four hours was offered at the endpoint of each phase During appetite testing sessions participants consumed an amount of food equal in total energy and macronutrient content at either one occasion at 800 am low-EF condition or spread evenly over two smaller eating occasions at 800 am and 1030 am high-EF condition Ratings of hunger desire to eat fullness thirst and nausea were made every 30 minutes using paper-and-pencil semi-anchored 100-mm Visual Analog Scales A composite appetite score was calculated as the mean of hunger desire to eat and 100-fullness The generalized estimating equation modification of linear regression was used to compare fasting plasma biomarkers and mean ratings of subjective appetite
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None