Ignite Creation Date:
2024-05-05 @ 11:59 AM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00201487
Status:
WITHDRAWN
Last Update Posted:
2013-10-31
First Post:
2005-09-16
Brief Title:
Choline Quantification in Breast Cancer by MRS
Sponsor:
Norwegian University of Science and Technology
Organization:
Norwegian University of Science and Technology
Study Overview
Official Title:
Choline Quantification in Breast Cancer by MRS
Status:
WITHDRAWN
Status Verified Date:
2013-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
We chose to use an exsisting NMR pulse sequence already established and available at the hospital
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Choline has been found in increased concentration in breast cancer patients Hypothesis The choline signal as observed by MRS is sensitive to treatment and a positive response to treatment will give a reduction in choline concentration
The purpose of this study is to establish methods for quantification of choline in breast cancer by MRS
The purpose of this study is to establish methods for quantification of choline in breast cancer by MRS
Detailed Description:
1 Establishment of new MRS sequence for choline quantification of choline This sequence is choline-selective and signals from water and lipids are suppressed simultaneously
2 Compare to different methods for choline quantification The first method is quantification through an external phantom standard containing a known concentration of choline The other method is based on the utilisation of internal water signal as a reference
Both calculations can be performed from the same MR exam Ten patients will be included in the study
2 Compare to different methods for choline quantification The first method is quantification through an external phantom standard containing a known concentration of choline The other method is based on the utilisation of internal water signal as a reference
Both calculations can be performed from the same MR exam Ten patients will be included in the study
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None