Ignite Creation Date:
2024-05-05 @ 11:59 AM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00207974
Status:
UNKNOWN
Last Update Posted:
2005-11-17
First Post:
2005-09-16
Brief Title:
Pharmacokinetic Study of Marine Active in Health Men
Sponsor:
China Medical University Hospital
Organization:
China Medical University Hospital
Study Overview
Official Title:
None
Status:
UNKNOWN
Status Verified Date:
2005-09
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hyperuricemia is often associated with metabolic syndrome which is a known precursor of atherosclerosis The Yaizu Suisankagaku Industry Company have developed industrial production named Marine Active Human clinical trials showed reduction of creatine phosphokinase activity and sero-uric acid Randomize double blind clinical trial is entrust to our hospital This study design is blood sampling from the health men who take 1 gm of marine active to analyse the pharmacokinetics of anserine
Detailed Description:
Hyperuricemia is a common metabolic disorder It can result from a decreased renal uric acid excretion increased urate production or both The classical association with clinical gout is well-known The principal indications for uric acid-lowering therapy including allopurinol probenecid and sulfinpyrazone are the patients with gout history macroscopic subcutaneous tophi frequent attacks of gouty arthritis or a documented state of uric acid overproduction Hyperuricemia is often associated with metabolic syndromewhich is known a percursor of atherosclerosis For the gout attack only 5 per year of the hyperuricemic population medical management is not indicated for patients without gouty arthritis Diet control is the leading way to control serum uric acid level but usually it is not enough So how to management hyperuricemia is important and is a potential managementHistidine-containing dipeptides such as Anserine and Carnosine have been studied extensively in recent years These dipeptides were shown to be effective in acting as buffering agents against protons developed during anaerobic exercise Anserine and Carnosine also have strong anti-oxidant activity anti-cancer activity immuno-response modulation fat reduction and enhanced wound healing functions The Yaizu Suisankagaku Industry Company have developed industrial production process to extract and purify the dipeptides from Bonito and Tuna The extract named Marine Active was able to offer anti-fatigue activity by animal trial data Human clinical trials showed reduction of creatine phosphokinase activity and sero-uric acid Randomize double blind clinical trial is entrust to our hospital This study design is blood sampling from the health men who take 1 gm of marine active to analyse the pharmacokinetics of anserine
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None